Associated Papers
Pathology of three ALS patients with FUS variants, including one likely benign Q23L variant lacking FUS inclusions.
Stenvall E et al.
Human Molecular Genetics, 2025
Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS.
Schweingruber C et al.
Nature Communications, 2025
FUS gene mutation in amyotrophic lateral sclerosis: a new case report and systematic review.
Xiao X et al.
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2024
Mutated FUS in familial amyotrophic lateral sclerosis involves multiple hnRNPs in the formation of neuronal cytoplasmic inclusions.
Honda H et al.
Journal of Neuropathology and Experimental Neurology, 2023
Characterising the Genetic Landscape of Amyotrophic Lateral Sclerosis: A Catalogue and Assessment of Over 1,000 Published Genetic Variants.
McCann EP et al.
Journal of Neuromuscular Diseases, 2023
Identifying amyloid-related diseases by mapping mutations in low-complexity protein domains to pathologies.
Murray KA et al.
Nature Structural & Molecular Biology, 2022
Bioinformatic identification of previously unrecognized amyloidogenic proteins.
Rosenberg GM et al.
The Journal of Biological Chemistry, 2022
A de novo c.1509dupA:p.R503fs mutation of FUS: report of a girl with sporadic juvenile amyotrophic lateral sclerosis.
Chen L et al.
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2020
The Occurrence of FUS Mutations in Pediatric Amyotrophic Lateral Sclerosis: A Case Report and Review of the Literature.
Picher-Martel V et al.
Journal of Child Neurology, 2020
The impact of rare variants in FUS in essential tremor.
Hopfner F et al.
Movement Disorders : Official Journal of the Movement Disorder Society, 2015
Mutational analysis of FUS gene and its structural and functional role in amyotrophic lateral sclerosis 6.
Kamaraj B et al.
Journal of Biomolecular Structure & Dynamics, 2015
The role of FUS gene variants in neurodegenerative diseases.
Deng H et al.
Nature Reviews. Neurology, 2014
Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons.
Wang WY et al.
Nature Neuroscience, 2013
Stress granules in neurodegeneration--lessons learnt from TAR DNA binding protein of 43 kDa and fused in sarcoma.
Bentmann E et al.
The Febs Journal, 2013
ALS mutant FUS disrupts nuclear localization and sequesters wild-type FUS within cytoplasmic stress granules.
Vance C et al.
Human Molecular Genetics, 2013
Using reference databases of genetic variation to evaluate the potential pathogenicity of candidate disease variants.
Kenna KP et al.
Human Mutation, 2013
TARDBP and FUS mutations associated with amyotrophic lateral sclerosis: summary and update.
Lattante S et al.
Human Mutation, 2013
FUS-related proteinopathies: lessons from animal models.
Lanson NA et al.
Brain Research, 2012
Dysfunction of constitutive and inducible ubiquitin-proteasome system in amyotrophic lateral sclerosis: implication for protein aggregation and immune response.
Bendotti C et al.
Progress in Neurobiology, 2012
TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration.
Fiesel FC et al.
The Febs Journal, 2011
FTD and ALS: a tale of two diseases.
Ferrari R et al.
Current Alzheimer Research, 2011
ALS-associated fused in sarcoma (FUS) mutations disrupt Transportin-mediated nuclear import.
Dormann D et al.
The Embo Journal, 2010
TDP-43 and FUS/TLS: emerging roles in RNA processing and neurodegeneration.
Lagier-Tourenne C et al.
Human Molecular Genetics, 2010
Mutations of FUS gene in sporadic amyotrophic lateral sclerosis.
Corrado L et al.
Journal of Medical Genetics, 2010
RNA-binding proteins in neurodegenerative disease: TDP-43 and beyond.
Hanson KA et al.
Wiley Interdisciplinary Reviews. Rna, 0