Associated Papers
Demographic, clinical and genetic characteristics of patients with amyotrophic lateral sclerosis from two specialised centres in Austria.
Keritam O et al.
Journal of Neurology, 2026
Co-occurrence of amyotrophic lateral sclerosis and multiple sclerosis: a rare but interesting association.
Jellinger KA
Journal of Neural Transmission (vienna, Austria : 1996), 2026
Axonal Eif5a hypusination controls local translation and mitigates defects in FUS-ALS.
Piol D et al.
Nature Neuroscience, 2026
Revisiting oligodendrocytes in amyotrophic lateral sclerosis using human multicellular stem cell models.
Mouhi S et al.
Trends in Cell Biology, 2025
Histone Post-Translational Modifications and DNA Double-Strand Break Repair in Neurodegenerative Diseases: An Epigenetic Perspective.
Yeasmin A et al.
Biology, 2025
Skin TDP-43 pathology as a candidate biomarker for predicting amyotrophic lateral sclerosis decades prior to motor symptom onset.
Waldron FM et al.
Biorxiv : the Preprint Server for Biology, 2025
Protein Structure-based FUS Mutational Subtypes Are Associated With Protein Mislocalization in Amyotrophic Lateral Sclerosis Patients.
Yang W et al.
Molecular Neurobiology, 2025
Altered Lipid Homeostasis in Mutant FUSR521H Astrocytes from HiPSCs.
Zhu Y et al.
Molecular Neurobiology, 2025
Blueprint of Collapse: Precision Biomarkers, Molecular Cascades, and the Engineered Decline of Fast-Progressing ALS.
Șerban M et al.
International Journal of Molecular Sciences, 2025
Perspectives in Amyotrophic Lateral Sclerosis: Biomarkers, Omics, and Gene Therapy Informing Disease and Treatment.
Bono N et al.
International Journal of Molecular Sciences, 2025
DNA nanoflower Oligo-PROTAC for targeted degradation of FUS to treat neurodegenerative diseases.
Ge R et al.
Nature Communications, 2025
Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS.
Schweingruber C et al.
Nature Communications, 2025
SARM1 is an essential component of neuronal Parthanatos.
Wu T et al.
Biorxiv : the Preprint Server for Biology, 2025
Exploring Protein Misfolding in Amyotrophic Lateral Sclerosis: Structural and Functional Insights.
Ivantsik O et al.
Biomedicines, 2025
Modelling Population Genetic Screening in Rare Neurodegenerative Diseases.
Spargo TP et al.
Biomedicines, 2025
A human-induced pluripotent stem cell (iPSC) line (SMUSHi006-A) from an ALS patient carrying a mutation c.1126C > T in the FUS gene.
Huang C et al.
Stem Cell Research, 2025
Amyotrophic lateral sclerosis caused by FUS mutations: advances with broad implications.
Moens TG et al.
The Lancet. Neurology, 2025
Therapeutic targeting of the oxidative stress generated by pathological molecular pathways in the neurodegenerative diseases, ALS and Huntington's.
Bajpai A et al.
European Journal of Pharmacology, 2025
TDP-43 as a potential retinal biomarker for neurodegenerative diseases.
Glashutter M et al.
Frontiers in Neuroscience, 2025
A systematic review and functional in-silico analysis of genes and variants associated with amyotrophic lateral sclerosis.
Arreola-Aldape CA et al.
Frontiers in Neuroscience, 2025
Case Report: A case of ALS type 6 associated with a FUS gene variant and right limb muscle weakness and atrophy as the initial symptom.
Zhan X et al.
Frontiers in Genetics, 2025
FUS-related amyotrophic lateral sclerosis-frontotemporal dementia and links to the DNA damage response: a systematic review.
Almalki S et al.
Frontiers in Molecular Neuroscience, 2025
Selective Inhibition of Cytosolic PARylation via PARG99: A Targeted Approach for Mitigating FUS-associated Neurodegeneration.
Kodavati M et al.
Biorxiv : the Preprint Server for Biology, 2024
Axonopathy Underlying Amyotrophic Lateral Sclerosis: Unraveling Complex Pathways and Therapeutic Insights.
Luan T et al.
Neuroscience Bulletin, 2024
Regulation of DNA damage response by RNA/DNA-binding proteins: Implications for neurological disorders and aging.
Kodavati M et al.
Ageing Research Reviews, 2024
Clinical and genetic characteristics of 1672 cases of amyotrophic lateral sclerosis in China: a single-center retrospective study.
Shen D et al.
Journal of Neurology, 2024
Synaptopathy: presynaptic convergence in frontotemporal dementia and amyotrophic lateral sclerosis.
Clayton EL et al.
Brain : a Journal of Neurology, 2024
Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS.
Vazquez-Sanchez S et al.
Molecular Neurodegeneration, 2024
Frontotemporal dementia-like disease progression elicited by seeded aggregation and spread of FUS.
Vazquez-Sanchez S et al.
Biorxiv : the Preprint Server for Biology, 2024
Impact of histone deacetylase inhibition and arimoclomol on heat shock protein expression and disease biomarkers in primary culture models of familial ALS.
Fernández Comaduran M et al.
Cell Stress & Chaperones, 2024
Plasma extracellular vesicle tau and TDP-43 as diagnostic biomarkers in FTD and ALS.
Chatterjee M et al.
Nature Medicine, 2024
The implications of physiological biomolecular condensates in amyotrophic lateral sclerosis.
Fakim H et al.
Seminars in Cell & Developmental Biology, 2024
FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease.
Kodavati M et al.
Nature Communications, 2024
Molecular hallmarks of ageing in amyotrophic lateral sclerosis.
Jagaraj CJ et al.
Cellular and Molecular Life Sciences : Cmls, 2024
The prognostic value of systematic genetic screening in amyotrophic lateral sclerosis patients.
He D et al.
Journal of Neurology, 2024
A transient protein folding response targets aggregation in the early phase of TDP-43-mediated neurodegeneration.
San Gil R et al.
Nature Communications, 2024
Mutations in FUS lead to synaptic dysregulation in ALS-iPSC derived neurons.
Shum C et al.
Stem Cell Reports, 2024
FUS gene mutation in amyotrophic lateral sclerosis: a new case report and systematic review.
Xiao X et al.
Amyotrophic Lateral Sclerosis & Frontotemporal Degeneration, 2024
Generation of a human induced pluripotent stem cell line (SMUSHi002-A) from an ALS patient carrying a heterozygous mutation c.1562G > A in the FUS gene.
Tang M et al.
Stem Cell Research, 2024
Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.
Zhu Y et al.
Acta Neuropathologica, 2024
IFNγ protects motor neurons from oxidative stress via enhanced global protein synthesis in FUS-associated amyotrophic lateral sclerosis.
Assoni AF et al.
Brain Pathology (zurich, Switzerland), 2024
Animal Models of FUS-Proteinopathy: A Systematic Review.
Rezvykh A et al.
Biochemistry. Biokhimiia, 2024
Diving deep: zebrafish models in motor neuron degeneration research.
Garg V et al.
Frontiers in Neuroscience, 2024
Astrocyte-Neuron Interactions Contributing to Amyotrophic Lateral Sclerosis Progression.
Jensen BK
Advances in Neurobiology, 2024
Cell and gene therapy for amyotrophic lateral sclerosis.
Paris A et al.
Handbook of Clinical Neurology, 2024