Varaico: Literature-Extracted Genetic Variants

Gene:G6PC2
Variant:p.S342C
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G6PC2

NM_021176.3:p.S342C

Associated Papers

G6PC2 controls glucagon secretion by defining the set point for glucose in pancreatic α cells.

Bahl V et al.

Science Translational Medicine, 2025

Somatic mutations reveal hyperactive Notch signaling and racial disparities in prurigo nodularis.

Rajeh A et al.

Medrxiv : the Preprint Server for Health Sciences, 2023

37808834 (PubMed )
Supplement: media-2.xlsx › pnSomatic_supplement_tableS2

Peptide ancestry informative markers in uterine neoplasms from women of European, African, and Asian ancestry.

Bateman NW et al.

Iscience, 2022

35036865 (PubMed )
Supplement: mmc2.xlsx › SupplementalTable1A

Susceptibility to type 2 diabetes may be modulated by haplotypes in G6PC2, a target of positive selection.

Al-Daghri NM et al.

Bmc Evolutionary Biology, 2017

Fasting glucose GWAS candidate region analysis across ethnic groups in the Multiethnic Study of Atherosclerosis (MESA).

Rasmussen-Torvik LJ et al.

Genetic Epidemiology, 2012

Mutations in G6PC2 do not contribute to monogenic forms of early infancy diabetes and beta cell dysfunction.

Bonnefond A et al.

Diabetologia, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."