Associated Papers
A covalent allosteric molecular glue suppresses NRF2-dependent cancer growth.
Roy N et al.
Cancer Discovery, 2025
Specific cancer types and prognosis in patients with variations in the KEAP1-NRF2 system: A retrospective cohort study.
Iwasaki T et al.
Cancer Science, 2024
Nrf2, A Target for Precision Oncology in Cancer Prognosis and Treatment.
Ngo HKC et al.
Journal of Cancer Prevention, 2023
NRF2 DLG Domain Mutations Identified in Japanese Liver Cancer Patients Affect the Transcriptional Activity in HCC Cell Lines.
Haque E et al.
International Journal of Molecular Sciences, 2021
Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.
Torrente L et al.
Redox Biology, 2020
32007910 (PubMed )
Supplement: mmc2.xlsx › Table_1_LuSCC
PIDD interaction with KEAP1 as a new mutation-independent mechanism to promote NRF2 stabilization and chemoresistance in NSCLC.
Ji L et al.
Scientific Reports, 2019
31455821 (PubMed )
Supplement: 41598_2019_48763_MOESM2_ESM.xlsx › B._Alteration_types_
A catalogue of somatic NRF2 gain-of-function mutations in cancer.
Kerins MJ et al.
Scientific Reports, 2018
30150714 (PubMed )
Supplement: 41598_2018_31281_MOESM3_ESM.xlsx › table1lungmuts
Tongue carcinoma infrequently harbor common actionable genetic alterations.
Tan DS et al.
Bmc Cancer, 2014
Multiplex genomic profiling of non-small cell lung cancers from the LETS phase III trial of first-line S-1/carboplatin versus paclitaxel/carboplatin: results of a West Japan Oncology Group study.
Okamoto I et al.
Oncotarget, 2014
24810493 (PubMed )
Supplement: oncotarget-05-2293-s001.pdf
Genotype analysis of the NRF2 gene mutation in lung cancer.
Sasaki H et al.
International Journal of Molecular Medicine, 2013
NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer.
Shibata T et al.
Neoplasia (new York, N.y.), 2011
Oncogenic NRF2 mutations in squamous cell carcinomas of oesophagus and skin.
Kim YR et al.
The Journal of Pathology, 2010
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