Varaico: Literature-Extracted Genetic Variants

Gene:GABPA
Variant:p.V122L
Back to variants list

GABPA

NM_002040.4:p.V122L

Associated Papers

A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants.

Aboulkassim T et al.

Cell Reports, 2023

KEAP1 Cancer Mutants: A Large-Scale Molecular Dynamics Study of Protein Stability.

Wilson CJ et al.

International Journal of Molecular Sciences, 2021

Molecular effects of cancer-associated somatic mutations on the structural and target recognition properties of Keap1.

Khan H et al.

The Biochemical Journal, 2015

25582950 (PubMed )
Supplement: supplement_1.pdf
Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."