Varaico: Literature-Extracted Genetic Variants

Gene:GAPDH
Variant:p.I33S
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GAPDH

NM_002046.7:p.I33S

Associated Papers

Recombination between fragile regions associated with chromosomal rearrangements in glioblastoma can be mediated by RAGs.

Paranjape A et al.

Iscience, 2025

Tumor-associated long non-coding RNAs show variable expression across diffuse gliomas and effect on cell growth upon silencing in glioblastoma.

Uusi-Mäkelä J et al.

Scientific Reports, 2025

40346283 (PubMed )
Supplement: 41598_2025_99984_MOESM2_ESM.xlsx › T98G_qPCR

IDH1 and ATRX mutations synergistically modulate cell proliferation and ferroptosis in glioblastoma cells.

Liu S et al.

American Journal of Cancer Research, 2025

Nuclear transport surveillance of p53 by nuclear pores in glioblastoma.

Ikliptikawati DK et al.

Cell Reports, 2023

DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma.

Taffoni C et al.

The Embo Journal, 2023

Epigenetically silenced apoptosis-associated tyrosine kinase (AATK) facilitates a decreased expression of Cyclin D1 and WEE1, phosphorylates TP53 and reduces cell proliferation in a kinase-dependent manner.

Woods ML et al.

Cancer Gene Therapy, 2022

35902728 (PubMed )
Supplement: 41417_2022_513_MOESM2_ESM.pdf

A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice.

Hattori EY et al.

Communications Biology, 2022

36085167 (PubMed )
Supplement: 42003_2022_3917_MOESM2_ESM.pdf

The effects of CHF6467, a new mutated form of NGF, on cell models of human glioblastoma. A comparison with wild-type NGF.

Lisi L et al.

Growth Factors (chur, Switzerland), 2022

35442129 (PubMed )
Supplement: supplement_1.docx

STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses.

Vila IK et al.

Cell Metabolism, 2022

Cyclin F drives proliferation through SCF-dependent degradation of the retinoblastoma-like tumor suppressor p130/RBL2.

Enrico TP et al.

Elife, 2021

Cancer-specific loss of TERT activation sensitizes glioblastoma to DNA damage.

Amen AM et al.

Proceedings of the National Academy of Sciences of the United States of America, 2021

33758097 (PubMed )
Supplement: pnas.2008772118.sapp.pdf

Synthetic Cannabinoids Induce Autophagy and Mitochondrial Apoptotic Pathways in Human Glioblastoma Cells Independently of Deficiency in TP53 or PTEN Tumor Suppressors.

Ellert-Miklaszewska A et al.

Cancers, 2021

Histone demethylase KDM4C controls tumorigenesis of glioblastoma by epigenetically regulating p53 and c-Myc.

Lee DH et al.

Cell Death & Disease, 2021

33462212 (PubMed )
Supplement: 41419_2020_3380_MOESM2_ESM.pdf

Gene expression profiling of glioblastoma cell lines depending on TP53 status after tumor-treating fields (TTFields) treatment.

Lee YJ et al.

Scientific Reports, 2020

Tandem repeats of the 5' flanking region of human MUC5AC have a role as a novel enhancer in MUC5AC gene expression.

Kageyama-Yahara N et al.

Biochemistry and Biophysics Reports, 2019

Epidermal growth factor receptor and ligand family expression and activity in glioblastoma.

von Achenbach C et al.

Journal of Neurochemistry, 2018

The brain-penetrant clinical ATM inhibitor AZD1390 radiosensitizes and improves survival of preclinical brain tumor models.

Durant ST et al.

Science Advances, 2018

Coordinated Splicing of Regulatory Detained Introns within Oncogenic Transcripts Creates an Exploitable Vulnerability in Malignant Glioma.

Braun CJ et al.

Cancer Cell, 2017

A functional dissection of PTEN N-terminus: implications in PTEN subcellular targeting and tumor suppressor activity.

Gil A et al.

Plos One, 2015

Bioinformatics Data Mining Approach Suggests Coexpression of AGTPBP1 with an ALS-linked Gene C9orf72.

Kitano S et al.

Journal of Central Nervous System Disease, 2015

Replication stress induces specific enrichment of RECQ1 at common fragile sites FRA3B and FRA16D.

Lu X et al.

Molecular Cancer, 2013

RNA editing of the Q/R site of GluA2 in different cultured cell lines that constitutively express different levels of RNA editing enzyme ADAR2.

Yamashita T et al.

Neuroscience Research, 2012

Analysis of the expression profile of Dickkopf-1 gene in human glioma and the association with tumor malignancy.

Zhou Y et al.

Journal of Experimental & Clinical Cancer Research : Cr, 2010

A novel p53 rescue compound induces p53-dependent growth arrest and sensitises glioma cells to Apo2L/TRAIL-induced apoptosis.

Weinmann L et al.

Cell Death and Differentiation, 2008

PIK3CA alterations in primary (de novo) and secondary glioblastomas.

Kita D et al.

Acta Neuropathologica, 2007

Improved silencing properties using small internally segmented interfering RNAs.

Bramsen JB et al.

Nucleic Acids Research, 2007

Brain angiogenesis inhibitor 1 is differentially expressed in normal brain and glioblastoma independently of p53 expression.

Kaur B et al.

The American Journal of Pathology, 2003

Molecular cloning and characterization of six novel isoforms of human Bim, a member of the proapoptotic Bcl-2 family.

U M et al.

Febs Letters, 2001

Transforming growth factor-beta-mediated p15(INK4B) induction and growth inhibition in astrocytes is SMAD3-dependent and a pathway prominently altered in human glioma cell lines.

Rich JN et al.

The Journal of Biological Chemistry, 1999

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."