Varaico: Literature-Extracted Genetic Variants

Gene:GAPDH
Variant:p.C152S
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GAPDH

NM_002046.7:p.C152S

Associated Papers

Analysis of the High-Order Conformational Changes in Glyceraldehyde-3-phosphate Dehydrogenase Induced by Nicotinamide Adenine Dinucleotide, Adenosine Triphosphate, and Oxidants.

Suzuki H et al.

Biochemistry, 2025

GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner.

Shi M et al.

Embo Reports, 2023

E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation.

Ravichandran KE et al.

The Embo Journal, 2022

36102610 (PubMed )
Supplement: EMBJ-41-e111318-s003.pdf

Mechanism of GAPDH Redox Signaling by H2O2 Activation of a Two-Cysteine Switch.

Hyslop PA et al.

International Journal of Molecular Sciences, 2022

Oxidized GAPDH transfers S-glutathionylation to a nuclear protein Sirtuin-1 leading to apoptosis.

Mustafa Rizvi SH et al.

Free Radical Biology & Medicine, 2021

Src-mediated phosphorylation of GAPDH regulates its nuclear localization and cellular response to DNA damage.

Ci S et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2020

Bioengineering of AAV2 capsid at specific serine, threonine, or lysine residues improves its transduction efficiency in vitro and in vivo.

Gabriel N et al.

Human Gene Therapy Methods, 2013

Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation.

Jia J et al.

Molecular Cell, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."