Varaico: Literature-Extracted Genetic Variants

Gene:GAPDH
Variant:p.C152S
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GAPDH

NM_002046.7:p.C152S

Associated Papers

Analysis of the High-Order Conformational Changes in Glyceraldehyde-3-phosphate Dehydrogenase Induced by Nicotinamide Adenine Dinucleotide, Adenosine Triphosphate, and Oxidants.

Suzuki H et al.

Biochemistry, 2025

GAPDH facilitates homologous recombination repair by stabilizing RAD51 in an HDAC1-dependent manner.

Shi M et al.

Embo Reports, 2023

E2/E3-independent ubiquitin-like protein conjugation by Urm1 is directly coupled to cysteine persulfidation.

Ravichandran KE et al.

The Embo Journal, 2022

36102610 (PubMed )
Supplement: EMBJ-41-e111318-s003.pdf

Mechanism of GAPDH Redox Signaling by H2O2 Activation of a Two-Cysteine Switch.

Hyslop PA et al.

International Journal of Molecular Sciences, 2022

Oxidized GAPDH transfers S-glutathionylation to a nuclear protein Sirtuin-1 leading to apoptosis.

Mustafa Rizvi SH et al.

Free Radical Biology & Medicine, 2021

Src-mediated phosphorylation of GAPDH regulates its nuclear localization and cellular response to DNA damage.

Ci S et al.

Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology, 2020

Protection of extraribosomal RPL13a by GAPDH and dysregulation by S-nitrosylation.

Jia J et al.

Molecular Cell, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."