Varaico: Literature-Extracted Genetic Variants

Gene:GBF1
Variant:p.E130A
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GBF1

NM_001377137.1:p.E130A

Associated Papers

The Arf-GEF GBF1 undergoes multi-domain structural shifts to activate Arf at the Golgi.

Meissner JM et al.

Frontiers in Cell and Developmental Biology, 2023

Regulating the regulators: role of phosphorylation in modulating the function of the GBF1/BIG family of Sec7 ARF-GEFs.

Walton K et al.

Febs Letters, 2020

Oligomerization of the Sec7 domain Arf guanine nucleotide exchange factor GBF1 is dispensable for Golgi localization and function but regulates degradation.

Bhatt JM et al.

American Journal of Physiology. Cell Physiology, 2016

Interactions between conserved domains within homodimers in the BIG1, BIG2, and GBF1 Arf guanine nucleotide exchange factors.

Ramaen O et al.

The Journal of Biological Chemistry, 2007

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."