Associated Papers
Downregulation of the kidney glucagon receptor, essential for renal function and systemic homeostasis, contributes to chronic kidney disease.
Wang MY et al.
Cell Metabolism, 2024
Well-differentiated G1 and G2 pancreatic neuroendocrine tumors: a meta-analysis of published expanded DNA sequencing data.
Andersen KØ et al.
Frontiers in Endocrinology, 2024
Glucagon cell hyperplasia and neoplasia: a recently recognized endocrine receptor disease.
Sipos B et al.
Endocrine-related Cancer, 2023
Diffuse, Adult-Onset Nesidioblastosis/Non-Insulinoma Pancreatogenous Hypoglycemia Syndrome (NIPHS): Review of the Literature of a Rare Cause of Hyperinsulinemic Hypoglycemia.
Dieterle MP et al.
Biomedicines, 2023
Molecular and in vivo phenotyping of missense variants of the human glucagon receptor.
van der Velden WJC et al.
The Journal of Biological Chemistry, 2022
The V369M Gcgr knock-in mice are a precision medicine model of mild Mahvash disease.
Yu R
The Biochemical Journal, 2020
Characterization of a naturally occurring mutation V368M in the human glucagon receptor and its association with metabolic disorders.
Lin G et al.
The Biochemical Journal, 2020
Increased SLC38A4 Amino Acid Transporter Expression in Human Pancreatic α-Cells After Glucagon Receptor Inhibition.
Kim J et al.
Endocrinology, 2019
The first pediatric case of glucagon receptor defect due to biallelic mutations in GCGR is identified by newborn screening of elevated arginine.
Li H et al.
Molecular Genetics and Metabolism Reports, 2018
Hypercalcemia in Glucagon Cell Hyperplasia and Neoplasia (Mahvash Syndrome): A New Association.
Gild ML et al.
The Journal of Clinical Endocrinology and Metabolism, 2018
Text Mining Genotype-Phenotype Relationships from Biomedical Literature for Database Curation and Precision Medicine.
Singhal A et al.
Plos Computational Biology, 2016
Glucagon receptor gene mutations with hyperglucagonemia but without the glucagonoma syndrome.
Miller HC et al.
World Journal of Gastrointestinal Surgery, 2015
Conditional deletion of Men1 in the pancreatic β-cell leads to glucagon-expressing tumor development.
Li F et al.
Endocrinology, 2015
Glucagon cell adenomatosis without glucagon receptor mutation.
Al-Sarireh B et al.
Pancreas, 2013
Rescue of a pathogenic mutant human glucagon receptor by pharmacological chaperones.
Yu R et al.
Journal of Molecular Endocrinology, 2012
Pancreatic neuroendocrine tumors in glucagon receptor-deficient mice.
Yu R et al.
Plos One, 2011
Homozygous P86S mutation of the human glucagon receptor is associated with hyperglucagonemia, alpha cell hyperplasia, and islet cell tumor.
Zhou C et al.
Pancreas, 2009
A natural inactivating mutant of human glucagon receptor exhibits multiple abnormalities in processing and signaling.
Yu R et al.
Endocrinologia Y Nutricion : Organo De La Sociedad Espanola De Endocrinologia Y Nutricion, 0