Varaico: Literature-Extracted Genetic Variants

Gene:GCK
Variant:p.M298I
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GCK

NM_000162.5:p.M298I

Associated Papers

Mutations in exons 10 and 11 of human glucokinase result in conformational variations in the active site of the structure contributing to poor substrate binding - explains hyperglycemia in type 2 diabetic patients.

Yellapu N et al.

Journal of Biomolecular Structure & Dynamics, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."