Varaico: Literature-Extracted Genetic Variants

Gene:GCKR
Variant:p.E300A
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GCKR

NM_001486.4:p.E300A

Associated Papers

Antidiabetic Disruptors of the Glucokinase-Glucokinase Regulatory Protein Complex Reorganize a Coulombic Interface.

Martinez JA et al.

Biochemistry, 2017

Mutations in exons 10 and 11 of human glucokinase result in conformational variations in the active site of the structure contributing to poor substrate binding - explains hyperglycemia in type 2 diabetic patients.

Yellapu N et al.

Journal of Biomolecular Structure & Dynamics, 2015

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."