Associated Papers
Domain II of the translation elongation factor eEF1A is required for Gcn2 kinase inhibition.
Ramesh R et al.
Febs Letters, 2020
Serine 577 is phosphorylated and negatively affects the tRNA binding and eIF2alpha kinase activities of GCN2.
Garcia-Barrio M et al.
The Journal of Biological Chemistry, 2002
The tRNA-binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation.
Qiu H et al.
The Embo Journal, 2001
Uncharged tRNA activates GCN2 by displacing the protein kinase moiety from a bipartite tRNA-binding domain.
Dong J et al.
Molecular Cell, 2000
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