Varaico: Literature-Extracted Genetic Variants

Gene:GGPS1
Variant:p.Y246D
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GGPS1

NM_004837.4:p.Y246D

Associated Papers

A somatic multiple myeloma mutation unravels a mechanism of oligomerization-mediated product inhibition in GGPPS.

Yehia R et al.

The Febs Journal, 2025

Engineering dimer mutants of human geranylgeranyl pyrophosphate synthase.

Ezekiel SJ et al.

Plos One, 2025

Inhibition of farnesyl pyrophosphate (FPP) and/or geranylgeranyl pyrophosphate (GGPP) biosynthesis and its implication in the treatment of cancers.

Waller DD et al.

Critical Reviews in Biochemistry and Molecular Biology, 2019

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."