Associated Papers
MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants.
Jamaluddin A et al.
Cell Reports, 2026
Whole-exome sequencing in children with dyslexia implicates rare variants in CLDN3 and ion channel genes.
Marianski K et al.
Human Genetics, 2025
Growth hormone treatment outcomes in children with genetic isolated growth hormone deficiency.
Aouchiche K et al.
European Journal of Pediatrics, 2025
MRAP2 potentiates GPCR signaling by conserved mechanisms that are disrupted by obesity-associated genetic variants.
Jamaluddin A et al.
Biorxiv : the Preprint Server for Biology, 2025
Loss-of-Function GHSR Variants Are Associated With Short Stature and Low IGF-I.
Punt LD et al.
The Journal of Clinical Endocrinology and Metabolism, 2025
The structure and function of the ghrelin receptor coding for drug actions.
Shiimura Y et al.
Nature Structural & Molecular Biology, 2025
Severe congenital hyperinsulinism with progressive neurological deterioration due to novel HADH-GHSR digenic mutations: the first case report.
Laaraje A et al.
Pediatric Endocrinology, Diabetes, and Metabolism, 2025
Ghrelin receptor signaling in health and disease: a biased view.
Gross JD et al.
Trends in Endocrinology and Metabolism: Tem, 2023
Diagnostic yield of a multigene sequencing approach in children classified as idiopathic short stature.
Andrade NLM et al.
Endocrine Connections, 2022
Binding Domain Characterization of Growth Hormone Secretagogue Receptor.
Sun Y et al.
Journal of Translational Internal Medicine, 2022
Genetic deletion of the ghrelin receptor (GHSR) impairs growth and blunts endocrine response to fasting in Ghsr-IRES-Cre mice.
Peris-Sampedro F et al.
Molecular Metabolism, 2021
Molecular recognition of an acyl-peptide hormone and activation of ghrelin receptor.
Wang Y et al.
Nature Communications, 2021
Allosteric modulation of ghrelin receptor signaling by lipids.
Damian M et al.
Nature Communications, 2021
Differential Diagnosis of the Short IGF-I-Deficient Child with Apparently Normal Growth Hormone Secretion.
Wit JM et al.
Hormone Research in Paediatrics, 2021
Metabolic insights from a GHSR-A203E mutant mouse model.
Torz LJ et al.
Molecular Metabolism, 2020
Heterozygous rare genetic variants in non-syndromic early-onset obesity.
Serra-Juhé C et al.
International Journal of Obesity (2005), 2020
Systematic analysis of the intersection of disease mutations with protein modifications.
Simpson CM et al.
Bmc Medical Genomics, 2019
Growth hormone secretagogue receptor constitutive activity impairs voltage-gated calcium channel-dependent inhibitory neurotransmission in hippocampal neurons.
Martínez Damonte V et al.
The Journal of Physiology, 2018
Comprehensive review of the duplication 3q syndrome and report of a patient with Currarino syndrome and de novo duplication 3q26.32-q27.2.
Dworschak GC et al.
Clinical Genetics, 2017
Molecular genetics of human obesity: A comprehensive review.
Singh RK et al.
Comptes Rendus Biologies, 2017
Molecular screening of a large cohort of Moroccan patients with congenital hypopituitarism.
Fritez N et al.
Clinical Endocrinology, 2015
The growth hormone secretagogue receptor: its intracellular signaling and regulation.
Yin Y et al.
International Journal of Molecular Sciences, 2014
GHS-R1a constitutive activity and its physiological relevance.
Mear Y et al.
Frontiers in Neuroscience, 2013
Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop.
Mokrosiński J et al.
The Journal of Biological Chemistry, 2012
The roles played by highly truncated splice variants of G protein-coupled receptors.
Wise H
Journal of Molecular Signaling, 2012
GH secretagogue receptor gene polymorphisms are associated with stature throughout childhood.
Riedl S et al.
European Journal of Endocrinology, 2012
Ghrelin and growth hormone secretagogue receptor (GHSR) genes are not commonly involved in growth or weight abnormalities in an Israeli pediatric population.
Hess O et al.
Journal of Pediatric Endocrinology & Metabolism : Jpem, 2012
Spectrum of insulin-like growth factor deficiency.
Wit JM et al.
Endocrine Development, 2012
Novel inactivating mutations in the GH secretagogue receptor gene in patients with constitutional delay of growth and puberty.
Pugliese-Pires PN et al.
European Journal of Endocrinology, 2011
G protein-coupled receptors: mutations and endocrine diseases.
Vassart G et al.
Nature Reviews. Endocrinology, 2011
Ghrelin plasma levels in patients with idiopathic short stature.
Iñiguez G et al.
Hormone Research in Paediatrics, 2011
Identification and functional analysis of novel human growth hormone secretagogue receptor (GHSR) gene mutations in Japanese subjects with short stature.
Inoue H et al.
The Journal of Clinical Endocrinology and Metabolism, 2011
Genetic causes and treatment of isolated growth hormone deficiency-an update.
Alatzoglou KS et al.
Nature Reviews. Endocrinology, 2010
Nucleotide polymorphisms and the 5'-UTR transcriptional analysis of the bovine growth hormone secretagogue receptor 1a (GHSR1a) gene.
Komatsu M et al.
Animal Science Journal = Nihon Chikusan Gakkaiho, 2010
Associations of GHSR gene polymorphisms with chicken growth and carcass traits.
Fang M et al.
Molecular Biology Reports, 2010
Associations of polymorphism within the GHSR gene with growth traits in Nanyang cattle.
Zhang B et al.
Molecular Biology Reports, 2009
Recessive isolated growth hormone deficiency and mutations in the ghrelin receptor.
Pantel J et al.
The Journal of Clinical Endocrinology and Metabolism, 2009
A genetic study of the ghrelin and growth hormone secretagogue receptor (GHSR) genes and stature.
Gueorguiev M et al.
Annals of Human Genetics, 2009
Genomic location of the bovine growth hormone secretagogue receptor (GHSR) gene and investigation of genetic polymorphism.
Colinet FG et al.
Animal Biotechnology, 2009
Constitutive activation of G protein-coupled receptors and diseases: insights into mechanisms of activation and therapeutics.
Tao YX
Pharmacology & Therapeutics, 2008
Polymorphisms of the ghrelin/obestatin gene and ghrelin levels in Chinese children with short stature.
Zou CC et al.
Clinical Endocrinology, 2008
Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor.
Holliday ND et al.
Molecular Endocrinology (baltimore, Md.), 2007
Four missense mutations in the ghrelin receptor result in distinct pharmacological abnormalities.
Liu G et al.
The Journal of Pharmacology and Experimental Therapeutics, 2007
The truncated ghrelin receptor polypeptide (GHS-R1b) acts as a dominant-negative mutant of the ghrelin receptor.
Leung PK et al.
Cellular Signalling, 2007
Ghrelin receptor mutations--too little height and too much hunger.
Holst B et al.
The Journal of Clinical Investigation, 2006
Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature.
Pantel J et al.
The Journal of Clinical Investigation, 2006