Varaico: Literature-Extracted Genetic Variants

Gene:GLP1R
Variant:p.P7L
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GLP1R

NM_002062.5:p.P7L

Associated Papers

Metabolic gene polymorphisms and type 2 diabetes mellitus risk: A systematic review and meta-analyses.

Indarto D et al.

Experimental and Therapeutic Medicine, 2026

Pharmacogenetics of incretin-based therapies.

Yaluri AS et al.

Postgraduate Medical Journal, 2025

Polygenic risk score and cluster-based analysis suggests links between type 2 diabetes and vascular dementia in the KARE study.

Dong W et al.

Nature Communications, 2025

Genetic variability in sodium-glucose cotransporter 2 and glucagon-like peptide 1 receptor effect on glycemic and pressure control in type 2 diabetes patients treated with SGLT2 inhibitors and GLP-1RA in the everyday clinical practice.

Tonin G et al.

Frontiers in Endocrinology, 2025

Whole exome sequencing and machine learning germline analysis of individuals presenting with extreme phenotypes of high and low risk of developing tobacco-associated lung adenocarcinoma.

Patiño-García A et al.

Ebiomedicine, 2024

38484556 (PubMed )
Supplement: mmc1.xlsx › Supp_Table_2

Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes.

Melchiorsen JU et al.

The Journal of Clinical Endocrinology and Metabolism, 2023

Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity.

Bairqdar A et al.

Journal of Personalized Medicine, 2023

Pharmacogenomics of GLP-1 receptor agonists: a genome-wide analysis of observational data and large randomised controlled trials.

Dawed AY et al.

The Lancet. Diabetes & Endocrinology, 2023

Discovery of 318 new risk loci for type 2 diabetes and related vascular outcomes among 1.4 million participants in a multi-ancestry meta-analysis.

Vujkovic M et al.

Nature Genetics, 2020

32541925 (PubMed )
Supplement: NIHMS1589535-supplement-1589535_Supp_Tab1-26.xlsx › T14

Genetic variants associated with glycemic response to treatment with dipeptidylpeptidase 4 inhibitors.

Űrgeová A et al.

Pharmacogenomics, 2020

Genetic variability in GLP-1 receptor is associated with inter-individual differences in weight lowering potential of liraglutide in obese women with PCOS: a pilot study.

Jensterle M et al.

European Journal of Clinical Pharmacology, 2015

Association of genetic variants of the incretin-related genes with quantitative traits and occurrence of type 2 diabetes in Japanese.

Enya M et al.

Molecular Genetics and Metabolism Reports, 2014

[Association between polymorphisms of TCF7L2 and type 2 diabetes with special reference to incretin action].

Enya M et al.

Nihon Rinsho. Japanese Journal of Clinical Medicine, 2011

Five missense mutations in glucagon-like peptide 1 receptor gene in Japanese population.

Tokuyama Y et al.

Diabetes Research and Clinical Practice, 2004

A small molecule ligand of the glucagon-like peptide 1 receptor targets its amino-terminal hormone binding domain.

Tibaduiza EC et al.

The Journal of Biological Chemistry, 2001

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."