Varaico: Literature-Extracted Genetic Variants

Gene:GLP1R
Variant:p.T149M
Back to variants list

GLP1R

NM_002062.5:p.T149M

Associated Papers

Metabolic gene polymorphisms and type 2 diabetes mellitus risk: A systematic review and meta-analyses.

Indarto D et al.

Experimental and Therapeutic Medicine, 2026

GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.

Lagou V et al.

Nature Genetics, 2023

37679419 (PubMed )
Supplement: 41588_2023_1462_MOESM6_ESM.xlsx › SuppTable12

Association between glucagon-like peptide-1 receptor gene polymorphism and treatment response to GLP1R agonists in Chinese patients with type 2 diabetes: a prospective cohort study.

Guan Z et al.

European Journal of Clinical Pharmacology, 2022

Ligand-Specific Factors Influencing GLP-1 Receptor Post-Endocytic Trafficking and Degradation in Pancreatic Beta Cells.

Fang Z et al.

International Journal of Molecular Sciences, 2020

rs6923761 gene variant in glucagon-like peptide 1 receptor: Allelic frequencies and influence on cardiovascular risk factors in a multicenter study of Castilla-Leon.

de Luis DA et al.

Clinical Nutrition (edinburgh, Scotland), 2018

Relation of the rs6923761 gene variant in glucagon-like peptide 1 receptor with weight, cardiovascular risk factor, and serum adipokine levels in obese female subjects.

de Luis DA et al.

Journal of Clinical Laboratory Analysis, 2015

Role of rs6923761 gene variant in glucagon-like peptide 1 receptor in basal GLP-1 levels, cardiovascular risk factor and serum adipokine levels in naïve type 2 diabetic patients.

de Luis DA et al.

Journal of Endocrinological Investigation, 2015

Polymorphisms of GLP-1 receptor gene and response to GLP-1 analogue in patients with poorly controlled type 2 diabetes.

Lin CH et al.

Journal of Diabetes Research, 2015

Association between Genetic Variants and Diabetes Mellitus in Iranian Populations: A Systematic Review of Observational Studies.

Khodaeian M et al.

Journal of Diabetes Research, 2015

Effect of rs6923761 gene variant of glucagon-like peptide 1 receptor on metabolic response and weight loss after a 3-month intervention with a hypocaloric diet.

de Luis DA et al.

Journal of Endocrinological Investigation, 2014

Cardiovascular risk factors and adipocytokines levels after two hypocaloric diets with different fat distribution in obese subjects and rs6923761 gene variant of glucagon-like peptide 1 receptor.

de Luis DA et al.

Journal of Endocrinological Investigation, 2014

[Roles of rs 6923761 gene variant in glucagon-like peptide 1 receptor on weight, cardiovascular risk factor and serum adipokine levels in morbid obese patients].

de Luis DA et al.

Nutricion Hospitalaria, 2014

Relation of the rs6923761 gene variant in glucagon-like peptide 1 receptor to metabolic syndrome in obese subjects.

de Luis DA et al.

Annals of Nutrition & Metabolism, 2014

Role of the rs6923761 gene variant in glucagon-like peptide 1 receptor gene on cardiovascular risk factors and weight loss after biliopancreatic diversion surgery.

de Luis DA et al.

Annals of Nutrition & Metabolism, 2014

Evaluation of weight loss and adipocytokine levels after two hypocaloric diets with different macronutrient distribution in obese subjects with the rs6923761 gene variant of glucagon-like peptide 1 receptor.

de Luis DA et al.

Annals of Nutrition & Metabolism, 2013

Individualized therapy for type 2 diabetes: clinical implications of pharmacogenetic data.

Mannino GC et al.

Molecular Diagnosis & Therapy, 2012

Residues within the transmembrane domain of the glucagon-like peptide-1 receptor involved in ligand binding and receptor activation: modelling the ligand-bound receptor.

Coopman K et al.

Molecular Endocrinology (baltimore, Md.), 2011

Spatial approximations between residues 6 and 12 in the amino-terminal region of glucagon-like peptide 1 and its receptor: a region critical for biological activity.

Chen Q et al.

The Journal of Biological Chemistry, 2010

Pharmacological characterization of human incretin receptor missense variants.

Fortin JP et al.

The Journal of Pharmacology and Experimental Therapeutics, 2010

A human glucagon-like peptide-1 receptor polymorphism results in reduced agonist responsiveness.

Beinborn M et al.

Regulatory Peptides, 2005

Five missense mutations in glucagon-like peptide 1 receptor gene in Japanese population.

Tokuyama Y et al.

Diabetes Research and Clinical Practice, 2004

Evaluation of weight loss and metabolic changes in diabetic patients treated with liraglutide, effect of RS 6923761 gene variant of glucagon-like peptide 1 receptor.

de Luis DA et al.

Journal of Diabetes and Its Complications, 0

Select a paper to view details
UCSC Genome Browser·Imprint·Privacy·Terms·Feedback·Email Updates·

Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."