Associated Papers
In vivo functional profiling and structural characterization of the human GLP1R A316T variant.
El Eid L et al.
Science Advances, 2026
RISING STARS: Effects of a GLP-1 receptor polymorphism on responses to liraglutide.
Mashayekhi M et al.
The Journal of Endocrinology, 2025
In vivo functional profiling and structural characterisation of the human Glp1r A316T variant.
El Eid L et al.
Biorxiv : the Preprint Server for Biology, 2025
The landscape of rare genetic variants in familial Waldenström macroglobulinemia.
Pemov A et al.
Blood Neoplasia, 2024
Association between the GLP1R A316T Mutation and Adolescent Idiopathic Scoliosis in French Canadian and Italian Cohorts.
Normand É et al.
Genes, 2024
GLP1R (glucagon-like-peptide-1 incretin receptor), diabetes and obesity phenotypes: An in silico approach revealed new pathogenic variants.
Knihs VM et al.
Diabetes & Metabolic Syndrome, 2024
Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes.
Melchiorsen JU et al.
The Journal of Clinical Endocrinology and Metabolism, 2023
Rare Variants of Obesity-Associated Genes in Young Adults with Abdominal Obesity.
Bairqdar A et al.
Journal of Personalized Medicine, 2023
Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity.
Gao W et al.
Nature Metabolism, 2023
GWAS of random glucose in 476,326 individuals provide insights into diabetes pathophysiology, complications and treatment stratification.
Lagou V et al.
Nature Genetics, 2023
Functionally Significant Variants in Genes Associated with Abdominal Obesity: A Review.
Bairqdar A et al.
Journal of Personalized Medicine, 2023
Large-scale exome array summary statistics resources for glycemic traits to aid effector gene prioritization.
Willems SM et al.
Wellcome Open Research, 2023
Association of GLP1R Polymorphisms With the Incretin Response.
Dorsey-Trevino EG et al.
The Journal of Clinical Endocrinology and Metabolism, 2022
The trans-ancestral genomic architecture of glycemic traits.
Chen J et al.
Nature Genetics, 2021
Identification of 28 new susceptibility loci for type 2 diabetes in the Japanese population.
Suzuki K et al.
Nature Genetics, 2019
Nonsynonymous Variants in PAX4 and GLP1R Are Associated With Type 2 Diabetes in an East Asian Population.
Kwak SH et al.
Diabetes, 2018
Genomic insights into the causes of type 2 diabetes.
Langenberg C et al.
Lancet (london, England), 2018
A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
Scott RA et al.
Science Translational Medicine, 2016
Recent progress in genetic and epigenetic research on type 2 diabetes.
Kwak SH et al.
Experimental & Molecular Medicine, 2016
Recent advances in understanding the genetic architecture of type 2 diabetes.
Mohlke KL et al.
Human Molecular Genetics, 2015
Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility.
Wessel J et al.
Nature Communications, 2015
Identification and functional characterization of G6PC2 coding variants influencing glycemic traits define an effector transcript at the G6PC2-ABCB11 locus.
Mahajan A et al.
Plos Genetics, 2015
Minireview: Signal bias, allosterism, and polymorphic variation at the GLP-1R: implications for drug discovery.
Koole C et al.
Molecular Endocrinology (baltimore, Md.), 2013
Pharmacological characterization of human incretin receptor missense variants.
Fortin JP et al.
The Journal of Pharmacology and Experimental Therapeutics, 2010