Varaico: Literature-Extracted Genetic Variants

Gene:GNAO1
Variant:p.R243H
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GNAO1

NM_020988.3:p.R243H

Associated Papers

Dominant Gα mutations in human disease: unifying mechanisms and treatment strategies.

Katanaev VL et al.

Embo Molecular Medicine, 2025

Mutated G proteins as drug targets.

Noorman van der Dussen K et al.

Trends in Pharmacological Sciences, 2025

Active Gαi/o mutants accelerate breast tumor metastasis via the c-Src pathway.

Lyu C et al.

Biorxiv : the Preprint Server for Biology, 2023

Registered report: Diverse somatic mutation patterns and pathway alterations in human cancers.

Sharma V et al.

Elife, 2016

The emerging mutational landscape of G proteins and G-protein-coupled receptors in cancer.

O'Hayre M et al.

Nature Reviews. Cancer, 2013

Specific roles of G(i) protein family members revealed by dissecting SST5 coupling in human pituitary cells.

Peverelli E et al.

Journal of Cell Science, 2013

Molecular basis of a novel oncogenic mutation in GNAO1.

Garcia-Marcos M et al.

Oncogene, 2011

Diverse somatic mutation patterns and pathway alterations in human cancers.

Kan Z et al.

Nature, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."