Associated Papers
Clinical outcomes of genomically guided trametinib monotherapy across cancer types: results from the IMPRESS-Norway trial.
Slørdahl KS et al.
Acta Oncologica (stockholm, Sweden), 2026
Adrenal mixed corticomedullary tumors: report of a case with molecular characterization and systematic review.
Pérez-Béliz E et al.
Virchows Archiv : an International Journal of Pathology, 2026
Molecular profiling in paediatric hepatocellular adenomas: phenotypic correlations and clinical significance.
Zhou Y et al.
Histopathology, 2026
Adrenal histologic and genetic characteristics of primary aldosteronism in late adulthood.
Blinder AR et al.
European Journal of Endocrinology, 2026
Multi-center multi-omics integration predicts individualized prognosis in medullary thyroid carcinoma.
Zhou Y et al.
Nature Communications, 2026
De novo GNAS-Gsα variant (p.Thr55Ala) with constitutive gain-of-function effects on AVPR2 and PTH1R signalings.
Ikeda M et al.
Journal of Human Genetics, 2026
Gαs variant detection discerns skeletal cell types involved in fibrous dysplasia pathogenesis.
Michel Z et al.
Bone, 2026
Six-Color Multiplex Digital PCR Assays for Comprehensive Screening and Identification of Multiple Driver Mutations Associated with Pancreatic Carcinogenesis.
Maeda C et al.
Clinical Chemistry, 2026
Molecular Characterization of Pancreatic Simple Mucinous Cysts With GNAS Mutation: A Case Report and Literature Review.
Mizukami S et al.
Pancreas, 2026
Comparative Analysis of a Dual DNA-RNA Panel and a DNA-Only Panel for Sarcoma: Real-World Data From a Nationwide Genomic Database.
Nakata E et al.
Cancer Science, 2026
Phylogenetic analysis of paired breast carcinomas identifies genetic events associated with clonal recurrence and invasive progression.
Kader T et al.
The Journal of Pathology, 2026
Tumor-normal sequencing reveals novel TP53 germline and clinically actionable somatic mutations in Nigerian breast cancer patients.
Onyia AF et al.
Cancer Genetics, 2026
Delayed Diagnosis of McCune-Albright Syndrome in Adulthood Revealed by Spinal Fibrous Dysplasia: Report of 2 Cases.
Rouach V et al.
Jcem Case Reports, 2026
Clinical and Biochemical Progression in a Patient With Cortisol-Producing Adenoma.
Nanba K et al.
Jcem Case Reports, 2026
Burosumab treatment for FGF23-related hypophosphatemia in a two-year-old girl with McCune-Albright syndrome.
Saito T et al.
Clinical Pediatric Endocrinology : Case Reports and Clinical Investigations : Official Journal of the Japanese Society for Pediatric Endocrinology, 2026
McCune-Albright Syndrome as a Rare Cause of Fanconi Syndrome and Kidney Failure: A Case Report and Literature Review.
Qian Le Boh GV et al.
Kidney Medicine, 2026
Clinical characteristics associated with somatic GNAS mutations in acromegaly: a systematic review and institutional experience.
Dillon BR et al.
Frontiers in Endocrinology, 2026
Mutant GNAS drives a pyloric metaplasia with tumor suppressive glycans in intraductal papillary mucinous neoplasia.
Quoc-Huy Trinh V et al.
Cell Reports, 2025
Ancestry-dependent patterns of somatic mosaicism and clonal hematopoiesis mutations in over 125,000 individuals reveal distinct cancer associations.
Colin-Leitzinger C et al.
Human Genomics, 2025
Clonal hematopoiesis in apparent treatment-resistant hypertension, insights from multiple medical centers and community-based cohorts.
Lv C et al.
Nature Aging, 2025
Personalized and Tumor Informed Circulating Tumor DNA Assay for Molecular Residual Disease Monitoring of Solid Malignancies.
Liu L et al.
Medcomm, 2025
Molecular pathology of intraductal papillary mucinous neoplasms of the pancreas: current understanding and perspectives on malignant progression.
Makino Y et al.
Journal of Gastroenterology, 2025
Paired tumor-normal sequencing provides insights into the CDKN2A-associated tumor spectrum.
Breen KE et al.
Npj Precision Oncology, 2025
Benign fibro-osseous lesions of the cranio-maxillofacial bones: an updated review with special emphasis on molecular pathogenesis.
Pandiar D et al.
Journal of Bone and Mineral Metabolism, 2025
Integrative analysis of genomic and transcriptomic data informs precancer progression in the pancreas.
Noller K et al.
Biorxiv : the Preprint Server for Biology, 2025
Effects of Krüppel-like factor 4 mutation on the clinicopathological characteristics and its related protein expressions in intraductal papillary mucinous neoplasm of the pancreas.
Nagamine Y et al.
Pancreatology : Official Journal of the International Association of Pancreatology (iap) ... [et Al.], 2025
Genomic profiling in hepatocellular carcinoma: a real-world retrospective analysis.
Salani F et al.
Esmo Open, 2025
Imprinting and skeletal disorders: lessons from pseudohypoparathyroidism and related disorders.
Iwasaki Y et al.
Journal of Bone and Mineral Research : the Official Journal of the American Society for Bone and Mineral Research, 2025
Segmental macular hyperpigmentation: new genes, new clinical implications.
Kinsler VA et al.
The British Journal of Dermatology, 2025
The Genomic Topography of Appendiceal Cancers: Our Current Understanding, Clinical Perspectives, and Future Directions.
Gironda DJ et al.
Cancers, 2025
Genomic alterations in pancreatic cystic neoplasms: from molecular characterization to precision clinical management.
Yang S et al.
International Journal of Surgery (london, England), 2025
Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors.
Tanaka J et al.
Molecular Oncology, 2025
Mucinous Cystadenocarcinomas of the Breast Exhibit Heterogeneous Genomic Profile as Triple Negative Breast Cancer, Harbor Alterations in PIK3CA, PTEN, AKT1, and GNAS Genes, and May Not Be Indolent.
Tondi Resta I et al.
International Journal of Surgical Pathology, 2025
Neutralization of Receptor activator of nuclear factor-κB ligand reduces fibrosis and promotes osteoblast differentiation in a mouse model of fibrous dysplasia driven by somatic expression of GnasR201H.
Ormsby RT et al.
Jbmr Plus, 2025
Single-cell analysis of human fibrous dysplasia bone reveals a fibrotic transcriptome and GNAS variants in endothelial, perivascular, and stromal cells.
Wentworth KL et al.
American Journal of Human Genetics, 2025
Dietary and Circulating Vitamins, Polymorphisms of Vitamin Metabolism Genes, and the Risk of Gastrointestinal Cancers: A Systematic Review and Meta-Analysis.
Wang XL et al.
Clinical and Translational Gastroenterology, 2025
Development and Performance Validation of a Comprehensive Liquid Biopsy Genotyping Panel for Pan-cancer Analysis.
Lim S et al.
Annals of Laboratory Medicine, 2025
Dominant Gα mutations in human disease: unifying mechanisms and treatment strategies.
Katanaev VL et al.
Embo Molecular Medicine, 2025
Mutated G proteins as drug targets.
Noorman van der Dussen K et al.
Trends in Pharmacological Sciences, 2025
Burosumab treatment for fibroblast growth factor-23-associated hypophosphatemia in an adult patient with severe fibrous dysplasia in McCune-Albright syndrome: case report and review of the literature.
Stelmachowska-Banaś M et al.
Jbmr Plus, 2025
Genotype-Phenotype Correlation in Fibrous Dysplasia/McCune-Albright Syndrome Patients With Craniofacial Lesions.
Xue J et al.
Oral Diseases, 2025
Unraveling the link between GNAS R201 mutation and colorectal cancer.
Behmanesh MA et al.
Scientific Reports, 2025
Clinical utility of liquid biopsy next-generation sequencing for advanced non-small cell lung cancer in the Netherlands.
de Bitter TJJ et al.
Scientific Reports, 2025
Genetic evaluation of pediatric pituitary adenomas and USP8-related genotype-phenotype correlations in Cushing's disease.
Zainab R et al.
Pituitary, 2025
MutationAssessor in cBioPortal.
Su Y et al.
Biorxiv : the Preprint Server for Biology, 2025