Varaico: Literature-Extracted Genetic Variants

Gene:GOLPH3
Variant:p.D130A
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GOLPH3

NM_022130.4:p.D130A

Associated Papers

Structure of trypanosome coat protein VSGsur and function in suramin resistance.

Zeelen J et al.

Nature Microbiology, 2021

33462435 (PubMed )
Supplement: EMS114721-supplement-Peer_reviews.pdf

Distinct roles of beta1 metal ion-dependent adhesion site (MIDAS), adjacent to MIDAS (ADMIDAS), and ligand-associated metal-binding site (LIMBS) cation-binding sites in ligand recognition by integrin alpha2beta1.

Valdramidou D et al.

The Journal of Biological Chemistry, 2008

Role of ADMIDAS cation-binding site in ligand recognition by integrin alpha 5 beta 1.

Mould AP et al.

The Journal of Biological Chemistry, 2003

Conformational changes in the integrin beta A domain provide a mechanism for signal transduction via hybrid domain movement.

Mould AP et al.

The Journal of Biological Chemistry, 2003

Integrin activation involves a conformational change in the alpha 1 helix of the beta subunit A-domain.

Mould AP et al.

The Journal of Biological Chemistry, 2002

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."