Varaico: Literature-Extracted Genetic Variants

Gene:GPBAR1
Variant:p.Q296*
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GPBAR1

NM_170699.3:p.Q296*

Associated Papers

A membrane-proximal, C-terminal α-helix is required for plasma membrane localization and function of the G Protein-coupled receptor (GPCR) TGR5.

Spomer L et al.

The Journal of Biological Chemistry, 2014

Association of bile acid receptor TGR5 variation and transit in health and lower functional gastrointestinal disorders.

Camilleri M et al.

Neurogastroenterology and Motility, 2011

TGR5 sequence variation in primary sclerosing cholangitis.

Hov JR et al.

Digestive Diseases (basel, Switzerland), 2011

Mutational characterization of the bile acid receptor TGR5 in primary sclerosing cholangitis.

Hov JR et al.

Plos One, 2010

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."