Varaico: Literature-Extracted Genetic Variants

Gene:GPR50
Variant:p.T4P
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GPR50

NM_004224.3:p.T4P

Associated Papers

Cyclic-di-GMP and ADP bind to separate domains of PilB as mutual allosteric effectors.

Dye KJ et al.

The Biochemical Journal, 2020

Identification of the lipopolysaccharide O-antigen biosynthesis priming enzyme and the O-antigen ligase in Myxococcus xanthus: critical role of LPS O-antigen in motility and development.

Pérez-Burgos M et al.

Molecular Microbiology, 2019

RNA Polymerase II Phosphorylated on CTD Serine 5 Interacts with the Spliceosome during Co-transcriptional Splicing.

Nojima T et al.

Molecular Cell, 2018

The type IV pilus assembly motor PilB is a robust hexameric ATPase with complex kinetics.

Sukmana A et al.

The Biochemical Journal, 2018

Novel mutations and structural deletions in TUBB8: expanding mutational and phenotypic spectrum of patients with arrest in oocyte maturation, fertilization or early embryonic development.

Chen B et al.

Human Reproduction (oxford, England), 2017

Crystal Structure of a Type IV Pilus Assembly ATPase: Insights into the Molecular Mechanism of PilB from Thermus thermophilus.

Mancl JM et al.

Structure (london, England : 1993), 2016

Zinc coordination is essential for the function and activity of the type II secretion ATPase EpsE.

Rule CS et al.

Microbiologyopen, 2016

The Conserved Tetratricopeptide Repeat-Containing C-Terminal Domain of Pseudomonas aeruginosa FimV Is Required for Its Cyclic AMP-Dependent and -Independent Functions.

Buensuceso RN et al.

Journal of Bacteriology, 2016

Mutation of the conserved calcium-binding motif in Neisseria gonorrhoeae PilC1 impacts adhesion but not piliation.

Cheng Y et al.

Infection and Immunity, 2013

PilMNOPQ from the Pseudomonas aeruginosa type IV pilus system form a transenvelope protein interaction network that interacts with PilA.

Tammam S et al.

Journal of Bacteriology, 2013

The platform protein is essential for type IV pilus biogenesis.

Takhar HK et al.

The Journal of Biological Chemistry, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."