Varaico: Literature-Extracted Genetic Variants

Gene:GPR50
Variant:p.G12D
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GPR50

NM_004224.3:p.G12D

Associated Papers

Targeting Ras with protein engineering.

Tomazini A et al.

Oncotarget, 2023

Molecular Biology and Therapeutic Perspectives for K-Ras Mutant Non-Small Cell Lung Cancers.

Cekani E et al.

Cancers, 2022

Enhanced interpretation of 935 hotspot and non-hotspot RAS variants using evidence-based structural bioinformatics.

Tripathi S et al.

Computational and Structural Biotechnology Journal, 2022

34976316 (PubMed )
Supplement: mmc1.docx

Two cases of severe congenital hypotrichosis caused by compound heterozygous mutations in the LSS gene.

Murata M et al.

The Journal of Dermatology, 2021

Robust p53 Stabilization Is Dispensable for Its Activation and Tumor Suppressor Function.

Kon N et al.

Cancer Research, 2021

Lysine Demethylase KDM6A in Differentiation, Development, and Cancer.

Tran N et al.

Molecular and Cellular Biology, 2020

A pan-cancer assessment of alterations of the kinase domain of ULK1, an upstream regulator of autophagy.

Kumar M et al.

Scientific Reports, 2020

Mutagenesis Scanning Uncovers Evolutionary Constraints on Tobacco Etch Potyvirus Membrane-Associated 6K2 Protein.

González R et al.

Genome Biology and Evolution, 2019

Novel mutations and structural deletions in TUBB8: expanding mutational and phenotypic spectrum of patients with arrest in oocyte maturation, fertilization or early embryonic development.

Chen B et al.

Human Reproduction (oxford, England), 2017

Cyclin D1 harboring the T286I mutation promotes oncogenic activation in endometrial cancer.

Ikeda Y et al.

Oncology Reports, 2013

Dacomitinib, an irreversible Pan-ErbB inhibitor significantly abrogates growth in head and neck cancer models that exhibit low response to cetuximab.

Ather F et al.

Plos One, 2013

Importance of the NCp7-like domain in the recognition of pre-let-7g by the pluripotency factor Lin28.

Desjardins A et al.

Nucleic Acids Research, 2012

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."