Varaico: Literature-Extracted Genetic Variants

Gene:GRB2
Variant:p.P206L
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GRB2

NM_002086.5:p.P206L

Associated Papers

Overexpression of GRB2 Enhances Epithelial to Mesenchymal Transition of A549 Cells by Upregulating SNAIL Expression.

Mitra P et al.

Cells, 2018

The elucidation of novel SH2 binding sites on PLD2.

Di Fulvio M et al.

Oncogene, 2006

GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex.

Carlier MF et al.

The Journal of Biological Chemistry, 2000

Molecular and cellular analysis of Grb2 SH3 domain mutants: interaction with Sos and dynamin.

Vidal M et al.

Journal of Molecular Biology, 1999

Growth factor receptor-bound protein 2 SH2/SH3 domain binding to CD28 and its role in co-signaling.

Kim HH et al.

The Journal of Biological Chemistry, 1998

Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains.

den Hertog J et al.

The Embo Journal, 1996

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."