Associated Papers
The Configuration of GRB2 in Protein Interaction and Signal Transduction.
Wang D et al.
Biomolecules, 2024
Overexpression of GRB2 Enhances Epithelial to Mesenchymal Transition of A549 Cells by Upregulating SNAIL Expression.
Mitra P et al.
Cells, 2018
A THEMIS:SHP1 complex promotes T-cell survival.
Paster W et al.
The Embo Journal, 2015
25535246 (PubMed )
Supplement: embj0034-0393-sd11.pdf
The elucidation of novel SH2 binding sites on PLD2.
Di Fulvio M et al.
Oncogene, 2006
GRB2 links signaling to actin assembly by enhancing interaction of neural Wiskott-Aldrich syndrome protein (N-WASp) with actin-related protein (ARP2/3) complex.
Carlier MF et al.
The Journal of Biological Chemistry, 2000
LAT: the ZAP-70 tyrosine kinase substrate that links T cell receptor to cellular activation.
Zhang W et al.
Cell, 1998
A lipid-anchored Grb2-binding protein that links FGF-receptor activation to the Ras/MAPK signaling pathway.
Kouhara H et al.
Cell, 1997
Tight association of GRB2 with receptor protein-tyrosine phosphatase alpha is mediated by the SH2 and C-terminal SH3 domains.
den Hertog J et al.
The Embo Journal, 1996
SH3 domain-mediated interaction of dystroglycan and Grb2.
Yang B et al.
The Journal of Biological Chemistry, 1995
The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.
Rozakis-Adcock M et al.
Nature, 1993
Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.
Li N et al.
Nature, 1993
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