Associated Papers
Functional variant at 19q13.3 confers nonsyndromic cleft palate susceptibility by regulating HIF3A.
Lou S et al.
Iscience, 2025
Functional Validation of Noncoding Variants Associated With Nonsyndromic Orofacial Cleft.
Zhu S et al.
Human Mutation, 2025
High incidence and geographic distribution of cleft palate in Finland are associated with the IRF6 gene.
Rahimov F et al.
Nature Communications, 2024
High incidence and geographic distribution of cleft palate cases in Finland are associated with a regulatory variant in IRF6.
Rahimov F et al.
Medrxiv : the Preprint Server for Health Sciences, 2024
Two rare variants reveal the significance of Grainyhead-like 3 Arginine 391 underlying non-syndromic cleft palate only.
Huang W et al.
Oral Diseases, 2023
Identification of Novel Risk Variants of Non-Syndromic Cleft Palate by Targeted Gene Panel Sequencing.
Dąbrowska J et al.
Journal of Clinical Medicine, 2023
Novel GRHL3 Variants in a South African Cohort With Cleft Lip and Palate.
Naicker T et al.
The Cleft Palate-craniofacial Journal : Official Publication of the American Cleft Palate-craniofacial Association, 2022
Reactivation of a developmental Bmp2 signaling center is required for therapeutic control of the murine periosteal niche.
Salazar VS et al.
Elife, 2019
Threonine 454 phosphorylation in Grainyhead-like 3 is important for its function and regulation by the p38 MAPK pathway.
Krzywinska E et al.
Biochimica Et Biophysica Acta. Molecular Cell Research, 2018
Association between a common missense variant in LOXL3 gene and the risk of non-syndromic cleft palate.
Khan MFJ et al.
Congenital Anomalies, 2018
Structural basis of gene regulation by the Grainyhead/CP2 transcription factor family.
Ming Q et al.
Nucleic Acids Research, 2018
Loss-of-Function GRHL3 Variants Detected in African Patients with Isolated Cleft Palate.
Eshete MA et al.
Journal of Dental Research, 2018
Grainyhead-like Transcription Factors in Craniofacial Development.
Carpinelli MR et al.
Journal of Dental Research, 2017
The Role of Noncoding Genetic Variation in Isolated Orofacial Clefts.
Thieme F et al.
Journal of Dental Research, 2017
A Genome-wide Association Study of Nonsyndromic Cleft Palate Identifies an Etiologic Missense Variant in GRHL3.
Leslie EJ et al.
American Journal of Human Genetics, 2016
Sequencing the GRHL3 Coding Region Reveals Rare Truncating Mutations and a Common Susceptibility Variant for Nonsyndromic Cleft Palate.
Mangold E et al.
American Journal of Human Genetics, 2016