Associated Papers
Identification of specific ligand-receptor interactions that govern binding and cooperativity of diverse modulators to a common metabotropic glutamate receptor 5 allosteric site.
Gregory KJ et al.
Acs Chemical Neuroscience, 2014
24528109 (PubMed )
Supplement: cn400225x_si_001.pdf
Probing the metabotropic glutamate receptor 5 (mGlu₅) positive allosteric modulator (PAM) binding pocket: discovery of point mutations that engender a "molecular switch" in PAM pharmacology.
Gregory KJ et al.
Molecular Pharmacology, 2013
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