Varaico: Literature-Extracted Genetic Variants

Gene:GRIK2
Variant:p.K525E
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GRIK2

NM_021956.5:p.K525E

Associated Papers

Damaging coding variants within kainate receptor channel genes are enriched in individuals with schizophrenia, autism and intellectual disabilities.

Koromina M et al.

Scientific Reports, 2019

Lessons from crystal structures of kainate receptors.

Møllerud S et al.

Neuropharmacology, 2017

Zinc potentiates GluK3 glutamate receptor function by stabilizing the ligand binding domain dimer interface.

Veran J et al.

Neuron, 2012

A nondesensitizing kainate receptor point mutant.

Nayeem N et al.

Molecular Pharmacology, 2009

Interface interactions modulating desensitization of the kainate-selective ionotropic glutamate receptor subunit GluR6.

Zhang Y et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."