Varaico: Literature-Extracted Genetic Variants

Gene:GRIK2
Variant:p.E738D
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GRIK2

NM_021956.5:p.E738D

Associated Papers

Cadmium opens GluK2 kainate receptors with cysteine substitutions at the M3 helix bundle crossing.

Wilding TJ et al.

The Journal of General Physiology, 2019

Agonist binding to the GluK5 subunit is sufficient for functional surface expression of heteromeric GluK2/GluK5 kainate receptors.

Fisher JL et al.

Cellular and Molecular Neurobiology, 2013

Distinct functional roles of subunits within the heteromeric kainate receptor.

Fisher JL et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2011

Subunit-specific desensitization of heteromeric kainate receptors.

Mott DD et al.

The Journal of Physiology, 2010

Glutamate receptor trafficking: endoplasmic reticulum quality control involves ligand binding and receptor function.

Mah SJ et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2005

Amino-acid residues involved in glutamate receptor 6 kainate receptor gating and desensitization.

Fleck MW et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2003

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."