Varaico: Literature-Extracted Genetic Variants

Gene:GRIN2A
Variant:p.K465E
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GRIN2A

NM_001134407.3:p.K465E

Associated Papers

Disruption of interdomain interactions in the glutamate binding pocket affects differentially agonist affinity and efficacy of N-methyl-D-aspartate receptor activation.

Maier W et al.

The Journal of Biological Chemistry, 2007

Point mutations identify the glutamate binding pocket of the N-methyl-D-aspartate receptor as major site of conantokin-G inhibition.

Wittekindt B et al.

Neuropharmacology, 2001

Identification of amino acid residues of the NR2A subunit that control glutamate potency in recombinant NR1/NR2A NMDA receptors.

Anson LC et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."