Varaico: Literature-Extracted Genetic Variants

Gene:GRIN2B
Variant:p.W607L
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GRIN2B

NM_000834.5:p.W607L

Associated Papers

Three-dimensional missense tolerance ratio analysis.

Perszyk RE et al.

Genome Research, 2021

34301626 (PubMed )
Supplement: supp_gr.275528.121_Supplemental_Dataset_2.xlsx › mutant_variant_Data

Disease-associated missense mutations in GluN2B subunit alter NMDA receptor ligand binding and ion channel properties.

Fedele L et al.

Nature Communications, 2018

Structural similarities between glutamate receptor channels and K(+) channels examined by scanning mutagenesis.

Panchenko VA et al.

The Journal of General Physiology, 2001

The selectivity filter of the N-methyl-D-aspartate receptor: a tryptophan residue controls block and permeation of Mg2+.

Williams K et al.

Molecular Pharmacology, 1998

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."