Varaico: Literature-Extracted Genetic Variants

Gene:GRIN2B
Variant:p.E413A
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GRIN2B

NM_000834.5:p.E413A

Associated Papers

Distinct Regulation of Early Trafficking of the NMDA Receptors by the Ligand-Binding Domains of the GluN1 and GluN2A Subunits.

Netolicky J et al.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2025

Three-dimensional missense tolerance ratio analysis.

Perszyk RE et al.

Genome Research, 2021

34301626 (PubMed )
Supplement: supp_gr.275528.121_Supplemental_Dataset_2.xlsx › mutant_variant_Data

The Extracellular Domains of GluN Subunits Play an Essential Role in Processing NMDA Receptors in the ER.

Horak M et al.

Frontiers in Neuroscience, 2021

The GluN2B-Glu413Gly NMDA receptor variant arising from a de novo GRIN2B mutation promotes ligand-unbinding and domain opening.

Wells G et al.

Proteins, 2018

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."