Varaico: Literature-Extracted Genetic Variants

Gene:GRK1
Variant:p.V10A
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GRK1

NM_002929.3:p.V10A

Associated Papers

Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1.

Chen Q et al.

Nature, 2021

Mapping the putative G protein-coupled receptor (GPCR) docking site on GPCR kinase 2: insights from intact cell phosphorylation and recruitment assays.

Beautrait A et al.

The Journal of Biological Chemistry, 2014

Activation of G protein-coupled receptor kinase 1 involves interactions between its N-terminal region and its kinase domain.

Huang CC et al.

Biochemistry, 2011

Recoverin binds exclusively to an amphipathic peptide at the N terminus of rhodopsin kinase, inhibiting rhodopsin phosphorylation without affecting catalytic activity of the kinase.

Higgins MK et al.

The Journal of Biological Chemistry, 2006

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."