Varaico: Literature-Extracted Genetic Variants

Gene:GRK2
Variant:p.S670A
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GRK2

NM_001619.5:p.S670A

Associated Papers

Structural insights into the catalytic cycle of G protein-coupled receptor kinase 5 and a possible regulatory site for potassium ion.

Chen Y et al.

The Journal of Biological Chemistry, 2025

GRK2-mediated AKT activation controls cell cycle progression and G2 checkpoint in a p53-dependent manner.

Rivas V et al.

Cell Death Discovery, 2024

Restricting mitochondrial GRK2 post-ischemia confers cardioprotection by reducing myocyte death and maintaining glucose oxidation.

Sato PY et al.

Science Signaling, 2018

Crystal Structure of G Protein-coupled Receptor Kinase 5 in Complex with a Rationally Designed Inhibitor.

Homan KT et al.

The Journal of Biological Chemistry, 2015

Constitutively active rhodopsin mutants causing night blindness are effectively phosphorylated by GRKs but differ in arrestin-1 binding.

Vishnivetskiy SA et al.

Cellular Signalling, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."