Associated Papers
GRK phosphorylation drives β-arrestin-independent internalization of chemokine receptor CXCR5.
Crecelius JM et al.
The Journal of Biological Chemistry, 2025
Genetic Catalytic Inactivation of GRK5 Impairs Cardiac Function in Mice Via Dysregulated P53 Levels.
Marzano F et al.
Jacc. Basic to Translational Science, 2022
Structure of a GRK5-Calmodulin Complex Reveals Molecular Mechanism of GRK Activation and Substrate Targeting.
Komolov KE et al.
Molecular Cell, 2021
Atomic Structure of GRK5 Reveals Distinct Structural Features Novel for G Protein-coupled Receptor Kinases.
Komolov KE et al.
The Journal of Biological Chemistry, 2015
G Protein-coupled receptor kinase 5 is localized to centrosomes and regulates cell cycle progression.
Michal AM et al.
The Journal of Biological Chemistry, 2012
G-protein-coupled receptor kinase 5 phosphorylates p53 and inhibits DNA damage-induced apoptosis.
Chen X et al.
The Journal of Biological Chemistry, 2010
Characterization of C-terminal tail determinants involved in CRTH2 receptor trafficking: identification of a recycling motif.
Roy SJ et al.
European Journal of Pharmacology, 2010
G Protein-coupled receptor kinases phosphorylate LRP6 in the Wnt pathway.
Chen M et al.
The Journal of Biological Chemistry, 2009
GRK5 deficiency leads to reduced hippocampal acetylcholine level via impaired presynaptic M2/M4 autoreceptor desensitization.
Liu J et al.
The Journal of Biological Chemistry, 2009
Nuclear and neuritic distribution of serine-129 phosphorylated alpha-synuclein in transgenic mice.
Schell H et al.
Neuroscience, 2009
The role of G-protein-coupled receptor kinase 5 in pathogenesis of sporadic Parkinson's disease.
Arawaka S et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience, 2006
Bimodal regulation of the human H1 histamine receptor by G protein-coupled receptor kinase 2.
Iwata K et al.
The Journal of Biological Chemistry, 2005
Development of a yeast bioassay to characterize G protein-coupled receptor kinases. Identification of an NH2-terminal region essential for receptor phosphorylation.
Noble B et al.
The Journal of Biological Chemistry, 2003
G-protein-coupled receptor (GPCR) kinase phosphorylation and beta-arrestin recruitment regulate the constitutive signaling activity of the human cytomegalovirus US28 GPCR.
Miller WE et al.
The Journal of Biological Chemistry, 2003