Varaico: Literature-Extracted Genetic Variants

Gene:GRM3
Variant:p.E870K
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GRM3

NM_000840.3:p.E870K

Associated Papers

Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains.

Mancinelli CD et al.

Proceedings of the National Academy of Sciences of the United States of America, 2024

38985766 (PubMed )
Supplement: pnas.2407744121.sapp.pdf

Control of G protein-coupled receptor function via membrane-interacting intrinsically disordered C-terminal domains.

Mancinelli C et al.

Biorxiv : the Preprint Server for Biology, 2024

Targeted DNA Sequencing of Cutaneous Melanoma Identifies Prognostic and Predictive Alterations.

Haugh AM et al.

Cancers, 2024

38611025 (PubMed )
Supplement: cancers-16-01347-s001.zip › cancers-2874995-supplementary.xlsx › TableS1

Dynamic ctDNA Mutational Complexity in Patients with Melanoma Receiving Immunotherapy.

Fitzgerald S et al.

Molecular Diagnosis & Therapy, 2023

37099071 (PubMed )
Supplement: 40291_2023_651_MOESM1_ESM.xlsx › Suppl._Table_2

Melanoma-associated GRM3 variants dysregulate melanosome trafficking and cAMP signaling.

Neto A et al.

Pigment Cell & Melanoma Research, 2018

High-throughput sequencing of the melanoma genome.

Kunz M et al.

Experimental Dermatology, 2013

Delving into somatic variation in sporadic melanoma.

Walia V et al.

Pigment Cell & Melanoma Research, 2012

A new mutation with staggering effects.

Harbour JW

Pigment Cell & Melanoma Research, 2011

Exon capture analysis of G protein-coupled receptors identifies activating mutations in GRM3 in melanoma.

Prickett TD et al.

Nature Genetics, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."