Varaico: Literature-Extracted Genetic Variants

Gene:GRN
Variant:p.G93A
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GRN

NM_002087.4:p.G93A

Associated Papers

Astrocytes: Dissecting Their Diverse Roles in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia.

Valori CF et al.

Cells, 2023

The spectrum of neurodevelopmental, neuromuscular and neurodegenerative disorders due to defective autophagy.

Deneubourg C et al.

Autophagy, 2022

The Role of VCP Mutations in the Spectrum of Amyotrophic Lateral Sclerosis-Frontotemporal Dementia.

Scarian E et al.

Frontiers in Neurology, 2022

Lipid-droplet-accumulating microglia represent a dysfunctional and proinflammatory state in the aging brain.

Marschallinger J et al.

Nature Neuroscience, 2020

ALS and FTD: an epigenetic perspective.

Belzil VV et al.

Acta Neuropathologica, 2016

Progranulin does not affect motor neuron degeneration in mutant SOD1 mice and rats.

Herdewyn S et al.

Neurobiology of Aging, 2013

Clinical genetics of amyotrophic lateral sclerosis: what do we really know?

Andersen PM et al.

Nature Reviews. Neurology, 2011

Progranulin is expressed within motor neurons and promotes neuronal cell survival.

Ryan CL et al.

Bmc Neuroscience, 2009

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."