Associated Papers
TDP-43 proteinopathies and neurodegeneration: insights from Caenorhabditis elegans models.
Pir GJ et al.
The Febs Journal, 2026
TDP-43 dysfunction leads to impaired proteostasis and predisposes mice to worse neurological outcomes after brain injury.
Rotunno MS et al.
Biorxiv : the Preprint Server for Biology, 2025
Structural insights and milestones in TDP-43 research: A comprehensive review of its pathological and therapeutic advances.
Dang M et al.
International Journal of Biological Macromolecules, 2025
Progranulin deficiency does not exacerbate TDP-43 pathology in TDP-43 transgenic mouse models.
Yang C et al.
Npj Dementia, 2025
Synaptopathy: presynaptic convergence in frontotemporal dementia and amyotrophic lateral sclerosis.
Clayton EL et al.
Brain : a Journal of Neurology, 2024
TDP-43 as a therapeutic target in neurodegenerative diseases: Focusing on motor neuron disease and frontotemporal dementia.
Babazadeh A et al.
Ageing Research Reviews, 2023
Emerging Therapies and Novel Targets for TDP-43 Proteinopathy in ALS/FTD.
Hayes LR et al.
Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics, 2022
Molecular Mechanisms Underlying TDP-43 Pathology in Cellular and Animal Models of ALS and FTLD.
Wood A et al.
International Journal of Molecular Sciences, 2021
Structural Transition, Function and Dysfunction of TDP-43 in Neurodegenerative Diseases.
Afroz T et al.
Chimia, 2019
The debated toxic role of aggregated TDP-43 in amyotrophic lateral sclerosis: a resolution in sight?
Hergesheimer RC et al.
Brain : a Journal of Neurology, 2019
Molecular Mechanisms of TDP-43 Misfolding and Pathology in Amyotrophic Lateral Sclerosis.
Prasad A et al.
Frontiers in Molecular Neuroscience, 2019
[Neuropathology of TDP-43 proteinopathy].
Akiyama H et al.
Brain and Nerve = Shinkei Kenkyu No Shinpo, 2013
Pathological mechanisms underlying TDP-43 driven neurodegeneration in FTLD-ALS spectrum disorders.
Janssens J et al.
Human Molecular Genetics, 2013
Amyotrophic lateral sclerosis: new insights into underlying molecular mechanisms and opportunities for therapeutic intervention.
Cozzolino M et al.
Antioxidants & Redox Signaling, 2012
Understanding the role of TDP-43 and FUS/TLS in ALS and beyond.
Da Cruz S et al.
Current Opinion in Neurobiology, 2011
Progranulin and TDP-43: mechanistic links and future directions.
Kumar-Singh S
Journal of Molecular Neuroscience : Mn, 2011
TDP-43 and FUS/TLS: cellular functions and implications for neurodegeneration.
Fiesel FC et al.
The Febs Journal, 2011
The role of mutant TAR DNA-binding protein 43 in amyotrophic lateral sclerosis and frontotemporal lobar degeneration.
Janssens J et al.
Biochemical Society Transactions, 2011
Phosphorylated and cleaved TDP-43 in ALS, FTLD and other neurodegenerative disorders and in cellular models of TDP-43 proteinopathy.
Arai T et al.
Neuropathology : Official Journal of the Japanese Society of Neuropathology, 2010
TAR DNA-binding protein 43 in neurodegenerative disease.
Chen-Plotkin AS et al.
Nature Reviews. Neurology, 2010
Frontotemporal dementia and amyotrophic lateral sclerosis-associated disease protein TDP-43 promotes dendritic branching.
Lu Y et al.
Molecular Brain, 2009
[Frontotemporal dementia (FTD) and genetic mutations including progranulin gene].
Arai T et al.
Rinsho Shinkeigaku = Clinical Neurology, 2008