Associated Papers
The EMCV protein 2B* is required for efficient cell lysis via both caspase-3-dependent and -independent pathways during infection.
Nguyen SK et al.
The Journal of General Virology, 2025
PARP1 inhibitors induce pyroptosis via caspase 3-mediated gasdermin E cleavage.
Kim C et al.
Biochemical and Biophysical Research Communications, 2023
Gasdermin E permits interleukin-1 beta release in distinct sublytic and pyroptotic phases.
Zhou B et al.
Cell Reports, 2021
Gasdermin E suppresses tumour growth by activating anti-tumour immunity.
Zhang Z et al.
Nature, 2020
Teleost Gasdermin E Is Cleaved by Caspase 1, 3, and 7 and Induces Pyroptosis.
Jiang S et al.
Journal of Immunology (baltimore, Md. : 1950), 2019
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