Varaico: Literature-Extracted Genetic Variants

Gene:GSTO1
Variant:p.A140D
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GSTO1

NM_004832.3:p.A140D

Associated Papers

The Role of GST Gene Polymorphic Variants in Antipsychotic-Induced Metabolic Disorders in Schizophrenia: A Pilot Study.

Mednova IA et al.

Pharmaceuticals (basel, Switzerland), 2025

GSTP1 and GSTO1 Variant Alleles Affect Susceptibility to Helicobacter pylori Infection and Severity of Helicobacter pylori-Associated Clinical Manifestations.

Pantic I et al.

International Journal of Molecular Sciences, 2025

Decoding the molecular landscape: HER2 and PD-L1 in advanced gastric cancer.

Yao J et al.

Frontiers in Immunology, 2025

40519936 (PubMed )
Supplement: Table1.xlsx › SNV

The Role of Glutathione Transferase Omega-Class Variant Alleles in Individual Susceptibility to Ovarian Cancer.

Simic P et al.

International Journal of Molecular Sciences, 2024

Single-Nucleotide Polymorphisms Associated with Mercury Levels and Neurological Symptoms: An Overview.

Perini JA et al.

Toxics, 2024

38535959 (PubMed )
Supplement: toxics-12-00226-s001.zip › toxics-2905208-supplementary.pdf

Interleukin-10 Gene Polymorphisms Modulate the Risk of Infertility in Chlamydia trachomatis Positive Kurdish Women in Erbil Province.

Ahmed Omar L et al.

Reports of Biochemistry & Molecular Biology, 2024

Effect of donor GSTM3 rs7483 genetic variant on tacrolimus elimination in the early period after liver transplantation.

Zhang T et al.

Peerj, 2024

39465171 (PubMed )
Supplement: peerj-12-18360-s002.7z › drug-metabolizing_enzymes_and_transporter__DMET__microarray › markerlist.xlsx › markerlist.TXT

Impact of Gene Modifiers on Cystic Fibrosis Phenotypic Profiles: A Systematic Review.

Ward A et al.

Human Mutation, 2024

40225935 (PubMed )
Supplement: 6165547.f1.zip › Supplementary_file_S1.pdf

The Polymorphisms in GSTO Genes (GSTO1 rs4925, GSTO2 rs156697, and GSTO2 rs2297235) Affect the Risk for Testicular Germ Cell Tumor Development: A Pilot Study.

Petrovic M et al.

Life (basel, Switzerland), 2023

The GSTO2 (rs156697) Polymorphism Modifies Diabetic Nephropathy Risk.

Pavlovic D et al.

Medicina (kaunas, Lithuania), 2023

Genetic dissection of glutathione S-transferase omega-1: identification of novel downstream targets and Alzheimer's disease pathways.

Jia Y et al.

Neural Regeneration Research, 2022

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM1_ESM.xlsx › sheet_1

GSTO1, GSTO2 and ACE2 Polymorphisms Modify Susceptibility to Developing COVID-19.

Djukic T et al.

Journal of Personalized Medicine, 2022

Airways glutathione S-transferase omega-1 and its A140D polymorphism are associated with severity of inflammation and respiratory dysfunction in cystic fibrosis.

Piaggi S et al.

Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society, 2021

Glutathione S-transferase gene polymorphic sequence variations: Association with risk and response to Imatinib among Chronic Myeloid Leukemia patients of Kashmir.

Baba SM et al.

International Journal of Laboratory Hematology, 2021

Glutathione-S-transferases genes-promising predictors of hepatic dysfunction.

Prysyazhnyuk V et al.

World Journal of Hepatology, 2021

A Genetic Study of Cerebral Atherosclerosis Reveals Novel Associations with NTNG1 and CNOT3.

Vattathil SM et al.

Genes, 2021

Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer.

Liu S et al.

Communications Biology, 2021

33907296 (PubMed )
Supplement: 42003_2021_2024_MOESM10_ESM.xlsx › Supplementary_Data_7

Human variability in glutathione-S-transferase activities, tissue distribution and major polymorphic variants: Meta-analysis and implication for chemical risk assessment.

Buratti FM et al.

Toxicology Letters, 2021

Polymorphisms in Genes Encoding Glutathione Transferase Pi and Glutathione Transferase Omega Influence Prostate Cancer Risk and Prognosis.

Santric V et al.

Frontiers in Molecular Biosciences, 2021

GSTT1 null and rs156697 Polymorphism in GSTO2 Influence the Risk and Therapeutic Outcome of B-Acute Lymphoblastic Leukemia Patients.

Baba SM et al.

Frontiers in Oncology, 2021

High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies.

Toulmonde M et al.

Ebiomedicine, 2020

33254023 (PubMed )
Supplement: mmc5.xlsx › UPS_somatic_mutations_filtered

Assessment of GSTO1 (A140D) and GSTO2 (N142D) Gene Polymorphisms in Iranian Women with Polycystic Ovarian Syndrome.

Miraghaee SS et al.

Reports of Biochemistry & Molecular Biology, 2020

Glutathione transferase genotypes may serve as determinants of risk and prognosis in renal cell carcinoma.

Pljesa-Ercegovac M et al.

Biofactors (oxford, England), 2020

GSTO1*CC Genotype (rs4925) Predicts Shorter Survival in Clear Cell Renal Cell Carcinoma Male Patients.

Radic T et al.

Cancers, 2019

Association analysis of Glutathione S-transferase omega-1 and omega-2 genetic polymorphisms and ischemic stroke risk in a Turkish population.

Bilgin E et al.

Neurological Research, 2019

Glutathione S-transferase omega gene polymorphism as a biomarker for human papilloma virus and cervical cancer in Iranian women

Zamani S et al.

Journal of the Turkish German Gynecological Association, 2018

Concomitance of Polymorphisms in Glutathione Transferase Omega Genes Is Associated with Risk of Clear Cell Renal Cell Carcinoma.

Radic TM et al.

The Tohoku Journal of Experimental Medicine, 2018

Genetic polymorphisms in amyotrophic lateral sclerosis: Evidence for implication in detoxification pathways of environmental toxicants.

Dardiotis E et al.

Environment International, 2018

NIPS, a 3D network-integrated predictor of deleterious protein SAPs, and its application in cancer prognosis.

Wang B et al.

Scientific Reports, 2018

29662108 (PubMed )
Supplement: 41598_2018_24286_MOESM1_ESM.pdf

Association of GSTO1 A140D and GSTO2 N142D Gene Variations with Breast Cancer Risk

Sharif MR et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2017

Xenobiotic/drug metabolizing enzyme and TP53 polymorphisms and clinical outcome in advanced nonsmall cell lung cancer patients.

Karacaoğlan V et al.

Turkish Journal of Medical Sciences, 2017

Relation of polymorphism of arsenic metabolism genes to arsenic methylation capacity and developmental delay in preschool children in Taiwan.

Hsieh RL et al.

Toxicology and Applied Pharmacology, 2017

Association of glutathione S-transferase omega polymorphism and spinocerebellar ataxia type 2.

Almaguer-Mederos LE et al.

Journal of the Neurological Sciences, 2017

Association of GSTO1 and GSTO2 Polymorphism with Risk of End-Stage Renal Disease Development and Patient Survival.

Cimbaljevic S et al.

Journal of Medical Biochemistry, 2016

Association between polymorphisms in arsenic metabolism genes and urinary arsenic methylation profiles in girls and boys chronically exposed to arsenic.

Recio-Vega R et al.

Environmental and Molecular Mutagenesis, 2016

Structure, function and disease relevance of Omega-class glutathione transferases.

Board PG et al.

Archives of Toxicology, 2016

Evaluation of Hybridization Capture Versus Amplicon-Based Methods for Whole-Exome Sequencing.

Samorodnitsky E et al.

Human Mutation, 2015

26110913 (PubMed )
Supplement: HUMU-36-903-s001.zip › humu22825-sup-00010-Table_S13.xlsx › Sheet1

Childhood Pre-B acute lymphoblastic leukemia and glutathione S-transferase omega 1 and 2 polymorphisms.

Rezazadeh D et al.

International Journal of Laboratory Hematology, 2015

Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract.

Agrawal SA et al.

Human Genetics, 2015

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.

Karageorgos I et al.

Human Genomics, 2015

26092435 (PubMed )
Supplement: 40246_2015_34_MOESM1_ESM.xlsx › FamilyA
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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."