Varaico: Literature-Extracted Genetic Variants

Gene:GSTO2
Variant:p.N142D
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GSTO2

NM_183239.2:p.N142D

Associated Papers

Thyroid/parathyroid function and fluoride: role of mitochondrial DNA and SOD genetic variations.

Sun Q et al.

Journal of Endocrinological Investigation, 2026

AS3MT Gene Variant Shows Association with Skin Lesions in an Arsenic Exposed Population of India.

Ghosh S et al.

Biological Trace Element Research, 2025

Glutathione S-transferase: A keystone in Parkinson's disease pathogenesis and therapy.

Padhan P et al.

Molecular and Cellular Neurosciences, 2025

GSTP1 and GSTO1 Variant Alleles Affect Susceptibility to Helicobacter pylori Infection and Severity of Helicobacter pylori-Associated Clinical Manifestations.

Pantic I et al.

International Journal of Molecular Sciences, 2025

The Role of Glutathione Transferase Omega-Class Variant Alleles in Individual Susceptibility to Ovarian Cancer.

Simic P et al.

International Journal of Molecular Sciences, 2024

Single-Nucleotide Polymorphisms Associated with Mercury Levels and Neurological Symptoms: An Overview.

Perini JA et al.

Toxics, 2024

38535959 (PubMed )
Supplement: toxics-12-00226-s001.zip › toxics-2905208-supplementary.pdf

Interleukin-10 Gene Polymorphisms Modulate the Risk of Infertility in Chlamydia trachomatis Positive Kurdish Women in Erbil Province.

Ahmed Omar L et al.

Reports of Biochemistry & Molecular Biology, 2024

The Polymorphisms in GSTO Genes (GSTO1 rs4925, GSTO2 rs156697, and GSTO2 rs2297235) Affect the Risk for Testicular Germ Cell Tumor Development: A Pilot Study.

Petrovic M et al.

Life (basel, Switzerland), 2023

The GSTO2 (rs156697) Polymorphism Modifies Diabetic Nephropathy Risk.

Pavlovic D et al.

Medicina (kaunas, Lithuania), 2023

Genetic dissection of glutathione S-transferase omega-1: identification of novel downstream targets and Alzheimer's disease pathways.

Jia Y et al.

Neural Regeneration Research, 2022

Genetic susceptibility of bladder cancer in the Lebanese population.

Kourie HR et al.

Bmc Medical Genomics, 2022

36253817 (PubMed )
Supplement: 12920_2022_1372_MOESM1_ESM.xlsx › sheet_1

GSTO1, GSTO2 and ACE2 Polymorphisms Modify Susceptibility to Developing COVID-19.

Djukic T et al.

Journal of Personalized Medicine, 2022

Glutathione S-transferase Omega 2 DD genotype is associated with an increased risk of sporadic amyotrophic lateral sclerosis in Chinese men.

Fan Z et al.

The Journal of International Medical Research, 2021

Targeted transcriptome analysis using synthetic long read sequencing uncovers isoform reprograming in the progression of colon cancer.

Liu S et al.

Communications Biology, 2021

33907296 (PubMed )
Supplement: 42003_2021_2024_MOESM10_ESM.xlsx › Supplementary_Data_7

Human variability in glutathione-S-transferase activities, tissue distribution and major polymorphic variants: Meta-analysis and implication for chemical risk assessment.

Buratti FM et al.

Toxicology Letters, 2021

Polymorphisms in Genes Encoding Glutathione Transferase Pi and Glutathione Transferase Omega Influence Prostate Cancer Risk and Prognosis.

Santric V et al.

Frontiers in Molecular Biosciences, 2021

Glutathione S-Transferase Omega-2 and Transforming Growth Factor-β1 Polymorphisms in Iranian Glaucoma Patients.

Bamdad S et al.

Journal of Ophthalmology, 2021

High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies.

Toulmonde M et al.

Ebiomedicine, 2020

33254023 (PubMed )
Supplement: mmc5.xlsx › UPS_somatic_mutations_filtered

Assessment of GSTO1 (A140D) and GSTO2 (N142D) Gene Polymorphisms in Iranian Women with Polycystic Ovarian Syndrome.

Miraghaee SS et al.

Reports of Biochemistry & Molecular Biology, 2020

Glutathione transferase genotypes may serve as determinants of risk and prognosis in renal cell carcinoma.

Pljesa-Ercegovac M et al.

Biofactors (oxford, England), 2020

Genetic Variants Associated with Chronic Kidney Disease in a Spanish Population.

Corredor Z et al.

Scientific Reports, 2020

GSTO1*CC Genotype (rs4925) Predicts Shorter Survival in Clear Cell Renal Cell Carcinoma Male Patients.

Radic T et al.

Cancers, 2019

Identification of novel non-synonymous variants associated with type 2 diabetes-related metabolites in Korean population.

Park TJ et al.

Bioscience Reports, 2019

31652446 (PubMed )
Supplement: BSR-2019-0078_supp.pdf

Extensive disruption of protein interactions by genetic variants across the allele frequency spectrum in human populations.

Fragoza R et al.

Nature Communications, 2019

31515488 (PubMed )
Supplement: 41467_2019_11959_MOESM11_ESM.xlsx › SD7_-_Drug_Targets

Genetic associations between genes in the renin-angiotensin-aldosterone system and renal disease: a systematic review and meta-analysis.

Smyth LJ et al.

Bmj Open, 2019

31048445 (PubMed )
Supplement: bmjopen-2018-026777supp001.pdf

Association analysis of Glutathione S-transferase omega-1 and omega-2 genetic polymorphisms and ischemic stroke risk in a Turkish population.

Bilgin E et al.

Neurological Research, 2019

Levels of DNA damage (Micronuclei) in patients suffering from chronic kidney disease. Role of GST polymorphisms.

Pastor S et al.

Mutation Research. Genetic Toxicology and Environmental Mutagenesis, 2018

Glutathione S-transferase omega gene polymorphism as a biomarker for human papilloma virus and cervical cancer in Iranian women

Zamani S et al.

Journal of the Turkish German Gynecological Association, 2018

Concomitance of Polymorphisms in Glutathione Transferase Omega Genes Is Associated with Risk of Clear Cell Renal Cell Carcinoma.

Radic TM et al.

The Tohoku Journal of Experimental Medicine, 2018

Effect of the GSTM1 gene deletion on glycemic variability, sympatho-vagal balance and arterial stiffness in patients with metabolic syndrome, but without diabetes.

Iorio A et al.

Diabetes Research and Clinical Practice, 2018

Association of GSTO1 A140D and GSTO2 N142D Gene Variations with Breast Cancer Risk

Sharif MR et al.

Asian Pacific Journal of Cancer Prevention : Apjcp, 2017

Relation of polymorphism of arsenic metabolism genes to arsenic methylation capacity and developmental delay in preschool children in Taiwan.

Hsieh RL et al.

Toxicology and Applied Pharmacology, 2017

Association of GSTO1 and GSTO2 Polymorphism with Risk of End-Stage Renal Disease Development and Patient Survival.

Cimbaljevic S et al.

Journal of Medical Biochemistry, 2016

Structure, function and disease relevance of Omega-class glutathione transferases.

Board PG et al.

Archives of Toxicology, 2016

Association of GSTO2 (N142D) Genetic Polymorphism and Acute Rejection of Liver.

Khosravi M et al.

International Journal of Organ Transplantation Medicine, 2016

Evaluation of Hybridization Capture Versus Amplicon-Based Methods for Whole-Exome Sequencing.

Samorodnitsky E et al.

Human Mutation, 2015

26110913 (PubMed )
Supplement: HUMU-36-903-s001.zip › humu22825-sup-00010-Table_S13.xlsx › Sheet1

Childhood Pre-B acute lymphoblastic leukemia and glutathione S-transferase omega 1 and 2 polymorphisms.

Rezazadeh D et al.

International Journal of Laboratory Hematology, 2015

Compound mouse mutants of bZIP transcription factors Mafg and Mafk reveal a regulatory network of non-crystallin genes associated with cataract.

Agrawal SA et al.

Human Genetics, 2015

Identification of cancer predisposition variants in apparently healthy individuals using a next-generation sequencing-based family genomics approach.

Karageorgos I et al.

Human Genomics, 2015

26092435 (PubMed )
Supplement: 40246_2015_34_MOESM1_ESM.xlsx › FamilyA

GSTO1*C/GSTO2*G haplotype is associated with risk of transitional cell carcinoma of urinary bladder.

Djukic T et al.

International Urology and Nephrology, 2015

Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction.

Lamontagne M et al.

Thorax, 2014

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."