Varaico: Literature-Extracted Genetic Variants

Gene:H2AC20
Variant:p.E92A
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H2AC20

NM_003517.3:p.E92A

Associated Papers

Post-translational modification of H2B C-terminal helix regulates nucleosome interactions and chromatin signaling.

Zhao Y et al.

Nucleic Acids Research, 2025

Ubiquitination of the histone variant mH2A1.2 prevents toxic RAD18 accumulation at a subset of genomic loci upon replication stress.

Galloy M et al.

Molecular Cell, 2025

Mechanism of nucleosomal H2A K13/15 monoubiquitination and adjacent dual monoubiquitination by RNF168.

Ai H et al.

Nature Chemical Biology, 2025

Native Mass Spectrometry Captures the Conformational Plasticity of Proteins with Low-Complexity Domains.

Osterholz H et al.

Jacs Au, 2025

Multifaceted regulation of sirtuin 2 (Sirt2) deacetylase activity.

Abeywardana MY et al.

The Journal of Biological Chemistry, 2024

Structures of H2A.Z-associated human chromatin remodelers SRCAP and TIP60 reveal divergent mechanisms of chromatin engagement.

Park G et al.

Biorxiv : the Preprint Server for Biology, 2024

Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A.

Deng Z et al.

Molecular Cell, 2023

Structural basis of paralog-specific KDM2A/B nucleosome recognition.

Spangler CJ et al.

Nature Chemical Biology, 2023

Tracking chromatin state changes using nanoscale photo-proximity labelling.

Seath CP et al.

Nature, 2023

Multivalent DNA and nucleosome acidic patch interactions specify VRK1 mitotic localization and activity.

Budziszewski GR et al.

Nucleic Acids Research, 2022

Histone H2B Mutations in Cancer.

Wan YCE et al.

Biomedicines, 2021

Oncohistone mutations enhance chromatin remodeling and alter cell fates.

Bagert JD et al.

Nature Chemical Biology, 2021

33649601 (PubMed )
Supplement: NIHMS1657731-supplement-1657731_Supp_Tab1.xlsx › Sheet1

Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch.

Lehmann LC et al.

Cell Reports, 2020

33357431 (PubMed )
Supplement: EMS117809-supplement-Supplementary_Materials.zip › 1-s2.0-S2211124720315187-mmc1.pdf

The molecular basis of tight nuclear tethering and inactivation of cGAS.

Zhao B et al.

Nature, 2020

Multivalent Interactions by the Set8 Histone Methyltransferase With Its Nucleosome Substrate.

Girish TS et al.

Journal of Molecular Biology, 2016

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."