Varaico: Literature-Extracted Genetic Variants

Gene:H2AX
Variant:p.K120R
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H2AX

NM_002105.3:p.K120R

Associated Papers

Synthetical lethality of Werner helicase and mismatch repair deficiency is mediated by p53 and PUMA in colon cancer.

Hao S et al.

Proceedings of the National Academy of Sciences of the United States of America, 2022

36508676 (PubMed )
Supplement: pnas.2211775119.sapp.pdf

Critical role of monoubiquitination of histone H2AX protein in histone H2AX phosphorylation and DNA damage response.

Wu CY et al.

The Journal of Biological Chemistry, 2011

Monoubiquitination of H2AX protein regulates DNA damage response signaling.

Pan MR et al.

The Journal of Biological Chemistry, 2011

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."