Associated Papers
Molecular features in gangliogliomas: a systematic review.
Pereira BJA et al.
Child's Nervous System : Chns : Official Journal of the International Society for Pediatric Neurosurgery, 2026
A novel iPSC model of Bryant-Li-Bhoj neurodevelopmental/neurodegenerative syndrome demonstrates the role of histone H3.3 in chromatin dynamics, neuronal differentiation, and maturation.
Sangree AK et al.
Journal of Translational Medicine, 2026
Integrated high-resolution copy number and histomolecular analysis of diffuse hemispheric glioma, H3 G34-mutant reveals universal TP53 abnormalities.
Trejo-Lopez JA et al.
Brain Pathology (zurich, Switzerland), 2026
Redefining Treatment Paradigms for Glioma in Adolescents and Young Adults: Population-Based Evidence for Molecular Classification.
Qu S et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2026
G34R cancer mutation alters the conformational ensemble and dynamics of the histone H3.3 tails.
Fuchs HA et al.
Nucleic Acids Research, 2026
H3-3A gene mutation analysis in giant cell tumor of bone and its histologic mimics: A single institutional study from India.
Uppin SG et al.
Annals of Diagnostic Pathology, 2026
Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma.
Fernandez NR et al.
Nature Genetics, 2026
H3.3G34W immunohistochemistry negative giant cell tumour of bone. Extended analysis of 35 such cases from a single institution in India.
Uppin SG et al.
Virchows Archiv : an International Journal of Pathology, 2025
Impact of Alzheimer's disease risk factors and local neuromelanin content on the transcriptomic landscape of the human locus coeruleus.
Mulvey B et al.
Biorxiv : the Preprint Server for Biology, 2025
Diffuse hemispheric glioma, H3 G34-mutant, a single centre experience and histopathological analysis.
Amer F et al.
Virchows Archiv : an International Journal of Pathology, 2025
Glial Malignancies.
Baker SJ et al.
Cold Spring Harbor Perspectives in Biology, 2025
A novel iPSC model of Bryant-Li-Bhoj neurodevelopmental/neurodegenerative syndrome demonstrates the role of histone H3.3 in chromatin dynamics, neuronal differentiation, and maturation.
Sangree AK et al.
Biorxiv : the Preprint Server for Biology, 2025
Implications of canonical histone H3.1 and histone variant H3.3 in cancer.
Wu P et al.
Open Biology, 2025
Diffuse Hemispheric Glioma, H3 G34-Mutant With Prominent Perivascular Invasion in a Middle-Aged Man: A Case Report and Literature Review of Middle-Aged and Elderly Cases.
Yuzawa S et al.
Neuropathology : Official Journal of the Japanese Society of Neuropathology, 2025
The clinical and molecular landscape of diffuse hemispheric glioma, H3 G34-mutant.
Le Rhun E et al.
Neuro-oncology, 2025
Clinical pathological characteristics correlation of H3F3A gene mutation in giant cell tumor of bone: a study of 96 cases.
Du J et al.
Translational Cancer Research, 2025
Outcomes From a Contemporary Mono-Institutional Cohort of Histone-Mutant Diffuse Hemispheric Glioma: A Rare and Aggressive Pediatric-Type High-Grade Primary Brain Tumor.
Jeeva M et al.
Brain Tumor Research and Treatment, 2025
G34R cancer mutation alters the conformational ensemble and dynamics of the histone H3.3 tails.
Fuchs HA et al.
Biorxiv : the Preprint Server for Biology, 2025
Next-Generation Sequencing in Oncology-A Guiding Compass for Targeted Therapy and Emerging Applications.
Galeș LN et al.
International Journal of Molecular Sciences, 2025
Alternative lengthening of telomere-based immortalization renders H3G34R-mutant diffuse hemispheric glioma hypersensitive to PARP inhibitor combination regimens.
Laemmerer A et al.
Neuro-oncology, 2025
H3.3-G34R Mutation-Mediated Epigenetic Reprogramming Leads to Enhanced Efficacy of Immune Stimulatory Gene Therapy in Diffuse Hemispheric Gliomas.
Garcia-Fabiani MB et al.
Biorxiv : the Preprint Server for Biology, 2025
Epigenetic reprogramming in pediatric gliomas: from molecular mechanisms to therapeutic implications.
Haase S et al.
Trends in Cancer, 2024
Rapid intraoperative amplicon sequencing of CNS tumor markers.
Evers M et al.
Computational and Structural Biotechnology Journal, 2024
HIRA protects telomeres against R-loop-induced instability in ALT cancer cells.
Lynskey ML et al.
Cell Reports, 2024
H3K27me3 Loss in Central Nervous System Tumors: Diagnostic, Prognostic, and Therapeutic Implications.
Angelico G et al.
Cancers, 2024
Multimodal magnetic resonance imaging (MRI) of juvenile and adult diffuse hemispheric gliomas with H3 G34-mutation: a case description.
Hu W et al.
Quantitative Imaging in Medicine and Surgery, 2024
Immune landscape of oncohistone-mutant gliomas reveals diverse myeloid populations and tumor-promoting function.
Andrade AF et al.
Nature Communications, 2024
Expanded phenotypic spectrum of neurodevelopmental and neurodegenerative disorder Bryant-Li-Bhoj syndrome with 38 additional individuals.
Layo-Carris DE et al.
European Journal of Human Genetics : Ejhg, 2024
Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospective cohort.
Hayashi N et al.
Acta Neuropathologica Communications, 2024
Deposition of onco-histone H3.3-G34W leads to DNA repair deficiency and activates cGAS/STING-mediated immune responses.
Mancarella D et al.
International Journal of Cancer, 2024
H3F3A K27M Mutations Drives a Repressive Transcriptome by Modulating Chromatin Accessibility, Independent of H3K27me3 in Diffuse Midline Glioma.
Bhattarai S et al.
Biorxiv : the Preprint Server for Biology, 2024
Diffuse hemispheric glioma with H3 p.K28M (K27M) mutation: Unusual non-midline presentation of diffuse midline glioma, H3 K27M-altered?
Donev K et al.
Journal of Neuropathology and Experimental Neurology, 2024
Histone 3.3-related chromatinopathy: missense variants throughout H3-3A and H3-3B cause a range of functional consequences across species.
Bryant L et al.
Human Genetics, 2024
Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors.
Giacomini G et al.
Nucleic Acids Research, 2024
Insights of Clinical Significance From 109 695 Solid Tumor Tissue-Based Comprehensive Genomic Profiles.
Heilmann AM et al.
The Oncologist, 2024
Intraoperative Integrated Diagnostic System for Malignant Central Nervous System Tumors.
Hayashi T et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research, 2024
Diagnostic challenges in complicated case of glioblastoma.
Aghova T et al.
Pathology Oncology Research : Por, 2024
Pediatric glioma histone H3.3 K27M/G34R mutations drive abnormalities in PML nuclear bodies.
Voon HPJ et al.
Genome Biology, 2023
From Pediatric to Adult Brain Cancer: Exploring Histone H3 Mutations in Australian Brain Cancer Patients.
Grebstad Tune B et al.
Biomedicines, 2023
Knockout tales: the versatile roles of histone H3.3 in development and disease.
Klein RH et al.
Epigenetics & Chromatin, 2023
Molecular profiling of pre- and post-treatment pediatric high-grade astrocytomas reveals acquired increased tumor mutation burden in a subset of recurrences.
Wood MD et al.
Acta Neuropathologica Communications, 2023
Targeting mitochondrial energetics reverses panobinostat- and marizomib-induced resistance in pediatric and adult high-grade gliomas.
Jane EP et al.
Molecular Oncology, 2023
A comprehensive genomic study of 390 H3F3A-mutant pediatric and adult diffuse high-grade gliomas, CNS WHO grade 4.
Williams EA et al.
Acta Neuropathologica, 2023
Pan-cancer atlas of somatic core and linker histone mutations.
Bonner ER et al.
Npj Genomic Medicine, 2023