Varaico: Literature-Extracted Genetic Variants

Gene:H3C2
Variant:p.G34V
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H3C2

NM_003537.4:p.G34V

Associated Papers

Histone H3.3 G34-mutant Diffuse Gliomas in Adults.

Wang L et al.

The American Journal of Surgical Pathology, 2022

A common classification framework for histone sequence alterations in tumours: an expert consensus proposal.

Leske H et al.

The Journal of Pathology, 2021

Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail.

Lowe BR et al.

Elife, 2021

H3 G34-mutant high-grade glioma.

Lim KY et al.

Brain Tumor Pathology, 2021

Effects of H3.3G34V mutation on genomic H3K36 and H3K27 methylation patterns in isogenic pediatric glioma cells.

Huang TY et al.

Acta Neuropathologica Communications, 2020

Low-Grade Gemistocytic Morphology in H3 G34R-Mutant Gliomas and Concurrent K27M Mutation: Clinicopathologic Findings.

Morris M et al.

Journal of Neuropathology and Experimental Neurology, 2020

Histone H3K27M Mutation Overrides Histological Grading in Pediatric Gliomas.

Mosaab A et al.

Scientific Reports, 2020

Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma.

Mackay A et al.

Cancer Cell, 2017

Evaluation of a novel antibody to define histone 3.3 G34R mutant brain tumours.

Haque F et al.

Acta Neuropathologica Communications, 2017

Detection of Histone H3 mutations in cerebrospinal fluid-derived tumor DNA from children with diffuse midline glioma.

Huang TY et al.

Acta Neuropathologica Communications, 2017

Targeting Epigenetic Pathways in the Treatment of Pediatric Diffuse (High Grade) Gliomas.

Vanan MI et al.

Neurotherapeutics : the Journal of the American Society for Experimental Neurotherapeutics, 2017

The genetic signatures of pediatric high-grade glioma: no longer a one-act play.

Diaz AK et al.

Seminars in Radiation Oncology, 2014

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.

Wu G et al.

Nature Genetics, 2014

Next-generation molecular genetics of brain tumours.

Suvà ML et al.

Current Opinion in Neurology, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."