Varaico: Literature-Extracted Genetic Variants

Gene:H3C2
Variant:p.G34R
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H3C2

NM_003537.4:p.G34R

Associated Papers

Implications of canonical histone H3.1 and histone variant H3.3 in cancer.

Wu P et al.

Open Biology, 2025

HIRA protects telomeres against R-loop-induced instability in ALT cancer cells.

Lynskey ML et al.

Cell Reports, 2024

Neuroradiological, genetic and clinical characteristics of histone H3 K27-mutant diffuse midline gliomas in the Kansai Molecular Diagnosis Network for CNS Tumors (Kansai Network): multicenter retrospective cohort.

Hayashi N et al.

Acta Neuropathologica Communications, 2024

Pan-cancer atlas of somatic core and linker histone mutations.

Bonner ER et al.

Npj Genomic Medicine, 2023

A Targeted Next-Generation Sequencing Panel to Genotype Gliomas.

Guarnaccia M et al.

Life (basel, Switzerland), 2022

Histone H3.3 G34-mutant Diffuse Gliomas in Adults.

Wang L et al.

The American Journal of Surgical Pathology, 2022

Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail.

Lowe BR et al.

Elife, 2021

H3 G34-mutant high-grade glioma.

Lim KY et al.

Brain Tumor Pathology, 2021

Infant High-Grade Gliomas Comprise Multiple Subgroups Characterized by Novel Targetable Gene Fusions and Favorable Outcomes.

Clarke M et al.

Cancer Discovery, 2020

Epigenetic heterogeneity in cancer.

Guo M et al.

Biomarker Research, 2019

The role of histone modifications and telomere alterations in the pathogenesis of diffuse gliomas in adults and children.

Lee J et al.

Journal of Neuro-oncology, 2017

Biomarker-based prognostic stratification of young adult glioblastoma.

Zhang RQ et al.

Oncotarget, 2016

Histone H3F3A and HIST1H3B K27M mutations define two subgroups of diffuse intrinsic pontine gliomas with different prognosis and phenotypes.

Castel D et al.

Acta Neuropathologica, 2015

Integrated analysis of pediatric glioblastoma reveals a subset of biologically favorable tumors with associated molecular prognostic markers.

Korshunov A et al.

Acta Neuropathologica, 2015

The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma.

Wu G et al.

Nature Genetics, 2014

Driver mutations of cancer epigenomes.

Roy DM et al.

Protein & Cell, 2014

Next-generation molecular genetics of brain tumours.

Suvà ML et al.

Current Opinion in Neurology, 2013

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."