Varaico: Literature-Extracted Genetic Variants

Gene:H3C3
Variant:p.G34R
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H3C3

NM_003531.3:p.G34R

Associated Papers

Implications of canonical histone H3.1 and histone variant H3.3 in cancer.

Wu P et al.

Open Biology, 2025

Stratified Medicine Pediatrics: Cell-Free DNA and Serial Tumor Sequencing Identifies Subtype-Specific Cancer Evolution and Epigenetic States.

George SL et al.

Cancer Discovery, 2025

39693475 (PubMed )
Supplement: cd-24-0916_supplementary_table_5_suppst5.xlsx › Sheet1

An exceptionally rare case of a diffuse midline glioma with concomitant H3.1 K27M and G34R mutations in the HIST1H3C (H3C3) gene.

Reisz Z et al.

Acta Neuropathologica Communications, 2025

HIRA protects telomeres against R-loop-induced instability in ALT cancer cells.

Lynskey ML et al.

Cell Reports, 2024

Surprising phenotypic diversity of cancer-associated mutations of Gly 34 in the histone H3 tail.

Lowe BR et al.

Elife, 2021

H3 G34-mutant high-grade glioma.

Lim KY et al.

Brain Tumor Pathology, 2021

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."