Associated Papers
HACE1 as a bridge between oxidative stress and autophagy.
Xia J et al.
Frontiers in Immunology, 2025
The HACE1 E3 ligase mediates RAC1-dependent control of mTOR signaling complexes.
Turgu B et al.
Embo Reports, 2023
Ubiquitin-independent proteasomal degradation of Spindlin-1 by the E3 ligase HACE1 contributes to cell-cell adhesion.
Palicharla VR et al.
Febs Letters, 2021
HACE1 Prevents Lung Carcinogenesis via Inhibition of RAC-Family GTPases.
Kogler M et al.
Cancer Research, 2020
How to Inactivate Human Ubiquitin E3 Ligases by Mutation.
Garcia-Barcena C et al.
Frontiers in Cell and Developmental Biology, 2020
Identification of cancer-associated missense mutations in hace1 that impair cell growth control and Rac1 ubiquitylation.
Andrio E et al.
Scientific Reports, 2017
HACE1 mediated K27 ubiquitin linkage leads to YB-1 protein secretion.
Palicharla VR et al.
Cellular Signalling, 2015
HACE1 deficiency causes an autosomal recessive neurodevelopmental syndrome.
Hollstein R et al.
Journal of Medical Genetics, 2015
Ubiquitylation of autophagy receptor Optineurin by HACE1 activates selective autophagy for tumor suppression.
Liu Z et al.
Cancer Cell, 2014
HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.
Zhang L et al.
Nature Communications, 2014
Hace1 controls ROS generation of vertebrate Rac1-dependent NADPH oxidase complexes.
Daugaard M et al.
Nature Communications, 2013
The E3 ligase HACE1 is a critical chromosome 6q21 tumor suppressor involved in multiple cancers.
Zhang L et al.
Nature Medicine, 2007
Differential expression of a novel ankyrin containing E3 ubiquitin-protein ligase, Hace1, in sporadic Wilms' tumor versus normal kidney.
Anglesio MS et al.
Human Molecular Genetics, 2004
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