Varaico: Literature-Extracted Genetic Variants

Gene:HCFC1
Variant:p.P134S
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HCFC1

NM_005334.3:p.P134S

Associated Papers

Interaction of MYC with host cell factor-1 is mediated by the evolutionarily conserved Myc box IV motif.

Thomas LR et al.

Oncogene, 2016

An emerging model for BAP1's role in regulating cell cycle progression.

Eletr ZM et al.

Cell Biochemistry and Biophysics, 2011

Role of the HCF-1 basic region in sustaining cell proliferation.

Mangone M et al.

Plos One, 2010

Sequence variants in host cell factor C1 are associated with Ménière's disease.

Vrabec JT et al.

Otology & Neurotology : Official Publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2008

Host cell factor-1 and E2F4 interact via multiple determinants in each protein.

Knez J et al.

Molecular and Cellular Biochemistry, 2006

Primary structure and compartmentalization of Drosophila melanogaster host cell factor.

Izeta A et al.

Gene, 2003

Host cell factor-1 interacts with and antagonizes transactivation by the cell cycle regulatory factor Miz-1.

Piluso D et al.

The Journal of Biological Chemistry, 2002

The herpesvirus transactivator VP16 mimics a human basic domain leucine zipper protein, luman, in its interaction with HCF.

Lu R et al.

Journal of Virology, 1998

A single-point mutation in HCF causes temperature-sensitive cell-cycle arrest and disrupts VP16 function.

Goto H et al.

Genes & Development, 1997

PBRM1 and BAP1 as novel targets for renal cell carcinoma.

Brugarolas J

Cancer Journal (sudbury, Mass.), 0

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Regarding the variants extracted from papers and shown text snippets from research papers, the following holds: "Some rights reserved. This work permits non-commercial use, distribution and reproduction in any medium, provided the original author and source are credited."